Recombinant Anti-CCR6 Vesicular Antibody, EV Displayed (VS-0425-YC641) (CAT#: VS-0425-YC641)

• Application
• ELISA, FC, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• CCR6

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Cynomolgus

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• C-C motif chemokine receptor 6

• Molecular Function
• G-protein coupled receptor, Receptor, Transducer

• Introduction
• CCR6 (C-C Motif Chemokine Receptor 6) is a Protein Coding gene. Diseases associated with CCR6 include Limited Scleroderma and Diffuse Cutaneous Systemic Sclerosis. Among its related pathways are Defensins and Akt Signaling. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity. An important paralog of this gene is CCR7.

• Alternative Names
• BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22

• Gene ID
• 1235

• UniProt ID
• P51684

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