Recombinant Anti-CD151 Vesicular Antibody, EV Displayed (VS-0425-YC232)

CAT#: VS-0425-YC232

The Recombinant Anti-CD151 Vesicular Antibody, EV Displayed (VS-0425-YC232) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD151-expressed cells or tissues. The CD151 is a membrane protein linked to nephropathy and epidermolysis bullosa. It participates in pathways like Collagen chain trimerization.

Gene Expression
Figure 1 Cerebral cortex Figure 2 Colon Figure 3 Liver Figure 4 Kidney Figure 5 Lymph node

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • CD151
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG1 kappa
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • CD151 molecule (Raph blood group)
  • Biological Process
  • Host-virus interaction
  • Molecular Function
  • Blood group antigen
  • Introduction
  • CD151 (CD151 Molecule (Raph Blood Group)) is a Protein Coding gene. Diseases associated with CD151 include Nephropathy With Pretibial Epidermolysis Bullosa And Deafness and Raph Blood Group System. Among its related pathways are Primary Focal Segmental Glomerulosclerosis FSGS and Collagen chain trimerization. Gene Ontology (GO) annotations related to this gene include integrin binding. An important paralog of this gene is TSPAN11.
  • Alternative Names
  • PETA-3, RAPH, SFA-1, TSPAN24
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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