Recombinant Anti-CD300A Vesicular Antibody, EV Displayed (VS-0425-YC268)
CAT#: VS-0425-YC268
The Recombinant Anti-CD300A Vesicular Antibody, EV Displayed (VS-0425-YC268) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD300A-expressed cells or tissues. The CD300A is a protein linked to innate immune system pathways and associations with Kabuki Syndrome.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line THP-1
Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10971/1944_A12_3_selected.jpg
Normal Tissue
Figure 2 IHC staining of human liver
Immunohistochemical staining of human liver shows strong cytoplasmic positivity in Kupffer cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11645/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11645/36629_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11645/36629_A_9_3.jpg
Normal Tissue
Figure 5 Testis
Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11645/36629_A_6_6.jpg
Normal Tissue
Figure 6 Bone marrow
Hematopoietic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11645/36629_B_5_4.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11645/36629_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (HMC-1, NB-4, RPMI-8226)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167851-CD300A
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD300A
- Host Animal
- Mouse
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein G
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD300a molecule
- Biological Process
- Cell adhesion, Immunity
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane, Vesicles, Cytosol
- Introduction
- CD300A (CD300a Molecule) is a Protein Coding gene. Diseases associated with CD300A include Kabuki Syndrome 1. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include phosphatidylserine binding and signaling receptor activity. An important paralog of this gene is CD300C.
- Alternative Names
- CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60
- Gene ID
- 11314
- UniProt ID
- Q9UGN4
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CD300A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3424z | Mouse Anti-CD300A Recombinant Antibody (clone 44C7) | WB, IP, IF, FC | Mouse IgG1 |
| MOB-0050MZ | Mouse Anti-CD300A Recombinant Antibody (clone NEM-261) | FC, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-104LC | Rat Anti-CD300A Recombinant Antibody (TAB-104LC) | FC, Block, WB, FuncS | Rat IgG2a |
| TAB-104LC-S(P) | Rat Anti-CD300A Recombinant Antibody; scFv Fragment (TAB-104LC-S(P)) | FC, WB | Rat scFv |
| TAB-105LC-S(P) | Mouse Anti-CD300A Recombinant Antibody; scFv Fragment (TAB-105LC-S(P)) | FC, WB | Mouse scFv |
| TAB-104LC-F(E) | Rat Anti-CD300A Recombinant Antibody; Fab Fragment (TAB-104LC-F(E)) | FC, WB | Rat Fab |
| TAB-105LC-F(E) | Mouse Anti-CD300A Recombinant Antibody; Fab Fragment (TAB-105LC-F(E)) | FC, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0551 | Hi-Affi™ Rabbit Anti-CD300A Recombinant Antibody (clone DS551AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY34 | CytoStream™ Rat Anti-CD300A Recombinant Antibody (clone 172224) | FC | Rat IgG2a, kappa |
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