Recombinant Anti-CD55 Vesicular Antibody, EV Displayed (VS-0425-YC184)

CAT#: VS-0425-YC184

The Recombinant Anti-CD55 Vesicular Antibody, EV Displayed (VS-0425-YC184) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD55-expressed cells or tissues. The CD55 is a protein with lipid binding and virus receptor activity, involved in pathways such as creation of C4 and C2 activators. It is associated with conditions like complement hyperactivation and angiopathic thrombosis.

Gene Expression
Figure 1 Cerebral cortex Figure 2 Lung Figure 3 Colon Figure 4 Testis Figure 5 RNA cell line category: Cell line enhanced (HeLa, HMC-1, PC-3, U-2197)

Recombinant Antibody

  • Application
  • ELISA, FC, Inhib, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • CD55
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG1
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • CD55 molecule (Cromer blood group)
  • Biological Process
  • Complement pathway, Host-virus interaction, Immunity, Innate immunity
  • Molecular Function
  • Blood group antigen, Host cell receptor for virus entry, Receptor
  • Introduction
  • CD55 (CD55 Molecule (Cromer Blood Group)) is a Protein Coding gene. Diseases associated with CD55 include Complement Hyperactivation, Angiopathic Thrombosis, And Protein-Losing Enteropathy and Blood Group, Cromer System. Among its related pathways are Creation of C4 and C2 activators and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include lipid binding and virus receptor activity. An important paralog of this gene is C4BPA.
  • Alternative Names
  • CR, CROM, DAF, TC
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