Recombinant Anti-CD55 Vesicular Antibody, EV Displayed (VS-0425-YC184) (CAT#: VS-0425-YC184)
The Recombinant Anti-CD55 Vesicular Antibody, EV Displayed (VS-0425-YC184) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD55-expressed cells or tissues. The CD55 is a protein with lipid binding and virus receptor activity, involved in pathways such as creation of C4 and C2 activators. It is associated with conditions like complement hyperactivation and angiopathic thrombosis.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_B_8_5.jpg
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_B_8_5.jpg
Figure 2 Lung
(Alveolar cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_1_4.jpg
(Alveolar cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_1_4.jpg
Figure 3 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_8_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_8_3.jpg
Figure 4 Testis
(Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_4_6.jpg
(Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_4_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (HeLa, HMC-1, PC-3, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
Figure 5 RNA cell line category: Cell line enhanced (HeLa, HMC-1, PC-3, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD55
- Host Animal
- Human
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD55 molecule (Cromer blood group)
- Biological Process
- Complement pathway, Host-virus interaction, Immunity, Innate immunity
- Molecular Function
- Blood group antigen, Host cell receptor for virus entry, Receptor
- Introduction
- CD55 (CD55 Molecule (Cromer Blood Group)) is a Protein Coding gene. Diseases associated with CD55 include Complement Hyperactivation, Angiopathic Thrombosis, And Protein-Losing Enteropathy and Blood Group, Cromer System. Among its related pathways are Creation of C4 and C2 activators and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include lipid binding and virus receptor activity. An important paralog of this gene is C4BPA.
- Alternative Names
- CR, CROM, DAF, TC
- Gene ID
- 1604
- UniProt ID
- P08174
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1214z | Mouse Anti-CD55 Recombinant Antibody (clone 43C4) | WB, ELISA, IHC | Mouse IgG1, λ |
| HPAB-0498-CN | Mouse Anti-CD55 Recombinant Antibody (HPAB-0498-CN) | ELISA, FC, Neut | Mouse IgG |
| FAMAB-1072CQ | Human Anti-CD55 Recombinant Antibody (clone BU14) | IHC | Human IgG1 |
| FAMAB-1073CQ | Mouse Anti-CD55 Recombinant Antibody (clone 67) | WB, FC, IF, IHC | Mouse IgG1 |
| VS2-QX14 | Mouse Anti-CD55 Recombinant Antibody (clone BRIC 110) | IHC, WB | Mouse IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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