Recombinant Anti-CD83 Vesicular Antibody, EV Displayed (VS-0425-YC173)

CAT#: VS-0425-YC173

The Recombinant Anti-CD83 Vesicular Antibody, EV Displayed (VS-0425-YC173) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD83-expressed cells or tissues. The CD83 is a protein involved in pathways related to hematopoietic stem cell differentiation and T cell receptor signaling, associated with diseases such as Plague.

Gene Expression
Figure 1 IF staining of human cell line RH-30 Figure 2 Tonsil Figure 3 Testis Figure 4 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, U-698)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • CD83
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • CD83 molecule
  • Cellular Localization
  • Nucleoplasm, Plasma membrane, Nucleoli, Golgi apparatus
  • Introduction
  • CD83 (CD83 Molecule) is a Protein Coding gene. Diseases associated with CD83 include Plague and Rift Valley Fever. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and T cell receptor signaling pathway.
  • Alternative Names
  • BL11, HB15
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