Recombinant Anti-CDH11 Vesicular Antibody, EV Displayed (VS-0425-YC241) (CAT#: VS-0425-YC241)

The Recombinant Anti-CDH11 Vesicular Antibody, EV Displayed (VS-0425-YC241) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CDH11-expressed cells or tissues. The CDH11 is a cadherin protein, associated with bone cysts and deafness, influencing signaling pathways.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Recombinant Antibody

  • Application
  • ELISA, FC, SPR, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • CDH11
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Cadherin 11
  • Biological Process
  • Cell adhesion
  • Introduction
  • CDH11 (Cadherin 11) is a Protein Coding gene. Diseases associated with CDH11 include Aneurysmal Bone Cysts and Deafness, Autosomal Recessive 89. Among its related pathways are ERK Signaling and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH8.
  • Alternative Names
  • CAD11, OB

Downloads

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NAB-514-sdAb Recombinant Anti-Human CDH11 VHH Single Domain Antibody ICC, FC, WB, FUNC Llama VHH

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