Recombinant Anti-CDH11 Vesicular Antibody, EV Displayed (VS-0425-YC241) (CAT#: VS-0425-YC241)
The Recombinant Anti-CDH11 Vesicular Antibody, EV Displayed (VS-0425-YC241) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CDH11-expressed cells or tissues. The CDH11 is a cadherin protein, associated with bone cysts and deafness, influencing signaling pathways.
Specific Inquiry
Normal Tissue
RNA Expression

Figure 1 Cerebral cortex
(Endothelial cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_B_9_5.jpg
(Endothelial cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_B_9_5.jpg

Figure 2 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_A_8_3.jpg
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_A_8_3.jpg

Figure 3 Kidney
(Cells in glomeruli
Staining:High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_A_7_5.jpg
(Cells in glomeruli
Staining:High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_A_7_5.jpg

Figure 4 Breast
(Glandular cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Myoepithelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_B_2_4.jpg
(Glandular cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Myoepithelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_B_2_4.jpg

Figure 5 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, fHDF/TERT166, HSkMC, PC-3, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140937-CDH11
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140937-CDH11
Recombinant Antibody
- Application
- ELISA, FC, SPR, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CDH11
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Cadherin 11
- Biological Process
- Cell adhesion
- Introduction
- CDH11 (Cadherin 11) is a Protein Coding gene. Diseases associated with CDH11 include Aneurysmal Bone Cysts and Deafness, Autosomal Recessive 89. Among its related pathways are ERK Signaling and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH8.
- Alternative Names
- CAD11, OB
- Gene ID
- 1009
- UniProt ID
- P55287
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Antibody Magnetic Beads
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-514-sdAb | Recombinant Anti-Human CDH11 VHH Single Domain Antibody | ICC, FC, WB, FUNC | Llama VHH |
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