Recombinant Anti-CEACAM1 Vesicular Antibody, EV Displayed (VS-0425-YC150)
CAT#: VS-0425-YC150
The Recombinant Anti-CEACAM1 Vesicular Antibody, EV Displayed (VS-0425-YC150) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CEACAM1-expressed cells or tissues. The CEACAM1 is a carcinoembryonic antigen gene family member, functioning in cell adhesion and implicated in tissue differentiation, angiogenesis, apoptosis, and immune response modulation.
Gene Expression
Normal Tissue
Figure 1 Colon
Enterocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2146/5911_A_8_3.jpg
Normal Tissue
Figure 2 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2146/5911_A_9_5.jpg
RNA Expression
Figure 3 RNA cell line category: Group enriched (CAPAN-2, Hep G2, OE19, RT4, SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000079385-CEACAM1
❮
❯
Recombinant Antibody
- Application
- Block, Cyt, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CEACAM1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CEA cell adhesion molecule 1
- Introduction
- This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
- Alternative Names
- BGP, BGP1, CD66a
- Gene ID
- 634
- UniProt ID
- P13688
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1253z | Mouse Anti-CEACAM1 Recombinant Antibody (clone 23A3) | ELISA, IHC, WB | Mouse IgG1, κ |
| HPAB-0470-CN | Mouse Anti-CEACAM1 Recombinant Antibody (HPAB-0470-CN) | ELISA, FC | Mouse IgG |
| HPAB-0471-CN | Mouse Anti-CEACAM1 Recombinant Antibody (clone 18-20) | ELISA, FC | Mouse IgG |
| FAMAB-1640CQ | Rat Anti-CEACAM1 Recombinant Antibody (clone YTH 71.3) | FC, IHC-Fr | Rat IgG2a |
| VS13-YC205 | Rabbit Anti-CEACAM1 Recombinant Antibody (VS13-YC205) | WB, IHC-P, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-014-F(E) | Anti-Human CEA Recombinant Antibody Fab Fragment (Arcitumomab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | Fab' - G1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-156CL | Human Anti-CEACAM1 Recombinant Antibody (TAB-156CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-439LC | Human Anti-CEACAM1 Recombinant Antibody (TAB-439LC) | ELISA, FC, IF | Human IgG |
| TAB-439LC-S(P) | Human Anti-CEACAM1 Recombinant Antibody; scFv Fragment (TAB-439LC-S(P)) | IF, FC, ELISA | Human scFv |
| TAB-439LC-F(E) | Human Anti-CEACAM1 Recombinant Antibody; Fab Fragment (TAB-439LC-F(E)) | IF, FC, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-443LC | Human Anti-CEACAM1 Recombinant Antibody (TAB-443LC) | Block, Cyt, ELISA, FC, FuncS | Chimeric (Mouse/Human) IgG1, κ |
| TAB-443LC-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (TAB-443LC-S(P)) | FC, SPR, IHC, ELISA | Mouse scFv |
| TAB-443LC-F(E) | Human Anti-CEACAM1 Recombinant Antibody; Fab Fragment (TAB-443LC-F(E)) | FC, SPR, IHC, ELISA | Chimeric (Mouse/Human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-453CQ | Mouse Anti-Ceacam1 Recombinant Antibody (clone MAb-CC1) | FC, WB, IP, IHC, ELISA, Block | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-454CQ | Mouse Anti-Ceacam1 Recombinant Antibody (clone CC1) | WB, Neut, FC, FuncS, IHC, IHC-Fr, IHC-P, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0648 | Hi-Affi™ Rabbit Anti-CEACAM1 Recombinant Antibody (clone DS648AB) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0470-CN-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (HPAB-0470-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0471-CN-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (clone 18-20) | ELISA, FC | Mouse scFv |
| HPAB-0472-CN-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (clone 6G5J) | ELISA, FC | Mouse scFv |
| HPAB-0372-YC-S(P) | Human Anti-CEACAM1 Recombinant Antibody; scFv Fragment (HPAB-0372-YC-S(P)) | ELISA, FC, Activ | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0470-CN-F(E) | Mouse Anti-CEACAM1 Recombinant Antibody; Fab Fragment (HPAB-0470-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0471-CN-F(E) | Mouse Anti-CEACAM1 Recombinant Antibody; Fab Fragment (clone 18-20) | ELISA, FC | Mouse Fab |
| HPAB-0472-CN-F(E) | Mouse Anti-CEACAM1 Recombinant Antibody; Fab Fragment (clone 6G5J) | ELISA, FC | Mouse Fab |
| HPAB-0372-YC-F(E) | Human Anti-CEACAM1 Recombinant Antibody; Fab Fragment (HPAB-0372-YC-F(E)) | ELISA, FC, Activ | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0572CQ | Rat Anti-CEACAM1 Recombinant Antibody (clone YTH71.3) | ELISA | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0517 | PE-B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC | |
| MHC-CN0518 | APC-B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC | |
| MHC-CN0519 | FITC-B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC | |
| MHC-CN0520 | B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1353 | Anti-Mouse CEACAM1 Immunohistochemistry Kit | IHC |
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