Recombinant Mouse Anti-CEACAM5 Antibody (clone 10D8-8G10-2A3) (CAT#: VS3-FY368)
This product is a recombinant mouse antibody that recognizes human CEACAM5 protein. The mAb was purified by affinity chromatography.
Specific Inquiry
IHC
Figure 1. Recombinant Mouse Anti-CEACAM5 Antibody (clone 10D8-8G10-2A3) in IHC.
Immunohistochemical analysis of paraffin-embedded tonsil using antibody to carcinoembryonic antigen CEA. High pressure and high temperature sodium citrate pH 6.0 for antigen retrieval.
Specifications
- Immunogen
- Synthesized peptide derived from human carcinoembryonic antigen(CEA)
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human CEACAM5
- Species Reactivity
- Human
- Clone
- 10D8-8G10-2A3
- Applications
- Immunohistochemistry-Paraffin
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity Chromatography Purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- PBS pH 7.3, 50% Glycerol, 0.5% BSA
- Preservative
- 0.02% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry: 1/100-1/500
Target
- Alternative Names
- Carcinoembryonic Antigen Related Cell Adhesion Molecule 5; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5; Meconium Antigen 100; CEA; Carcinoembryonic Antigen; CD66e Antigen; CD66e
- Gene ID
- 1048
- UniProt ID
- P06731
- Sequence Similarities
- Belongs to the immunoglobulin superfamily. CEA family.
- Cellular Localization
- Cell membrane, Membrane
- Post Translation Modifications
- Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
- Protein Refseq
- NP_001278413.1; NP_001295327.1; NP_004354.3
- Function
- Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933).
Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308).
Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050).
(Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
Recommended Products
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1138z | Mouse Anti-CEACAM5 Recombinant Antibody (clone 32B10) | WB, IP, IF, FC | Mouse IgG1, κ |
| HPAB-0243-FY | Human Anti-CEACAM5 Recombinant Antibody (HPAB-0243-FY) | ELISA, FuncS | Chimeric (mouse/human) IgG1 |
| ZG-0391F | Mouse Anti-CEACAM5 Recombinant Antibody (ZG-0391F) | WB, IF, ELISA | Mouse IgG |
| VS3-QX225 | Mouse Anti-CEACAM5 Recombinant Antibody (clone 1C7) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-QX226 | Mouse Anti-CEACAM5 Recombinant Antibody (clone 3G12) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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