Recombinant Anti-CLCNKA Vesicular Antibody, EV Displayed (VS-0425-YC425) (CAT#: VS-0425-YC425)

The Recombinant Anti-CLCNKA Vesicular Antibody, EV Displayed (VS-0425-YC425) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CLCNKA-expressed cells or tissues. The CLCNKA belongs to the chloride channel family, participating in kidney salt reabsorption and inner ear functions.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • CLCNKA
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Bovine
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Chloride voltage-gated channel Ka
  • Biological Process
  • Ion transport, Transport
  • Molecular Function
  • Chloride channel, Ion channel, Voltage-gated channel
  • Introduction
  • This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CLCNKB

Downloads

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CAT Product Name Application Type
PABC-270 Mouse Anti-CLCNKA Recombinant Antibody (clone 25E7) ELISA, IF Mouse IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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