Recombinant Anti-CLDN6 Vesicular Antibody, EV Displayed (VS-0425-YC130)
CAT#: VS-0425-YC130
The Recombinant Anti-CLDN6 Vesicular Antibody, EV Displayed (VS-0425-YC130) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CLDN6-expressed cells or tissues. The CLDN6 is a component of tight junction strands, which form a physical barrier to prevent solutes and water from passing freely through cellular spaces. It serves as an entry cofactor for hepatitis C virus and may be involved in esophageal tumorigenesis.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Group enriched (BEWO, CACO-2, NTERA-2, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184697-CLDN6
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Recombinant Antibody
- Application
- Cyt, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CLDN6
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Claudin 6
- Biological Process
- Host-virus interaction
- Molecular Function
- Host cell receptor for virus entry, Receptor
- Introduction
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis.
- Gene ID
- 9074
- UniProt ID
- P56747
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3290z | Mouse Anti-CLDN6 Recombinant Antibody (clone 21D9) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| HPAB-0078-FY | Mouse Anti-CLDN6 Recombinant Antibody (HPAB-0078-FY) | Activ | Mouse IgG2a, κ |
| HPAB-1496-FY | Mouse Anti-CLDN6 Recombinant Antibody (HPAB-1496-FY) | ELISA, FC | Mouse IgG2a, κ |
| HPAB-1497-FY | Mouse Anti-CLDN6 Recombinant Antibody (HPAB-1497-FY) | ELISA, FC | Mouse IgG2a, κ |
| VS7-HM748 | Mouse Anti-CLDN6 Recombinant Antibody (clone 8G5D2) | FCM | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-507LC | Mouse Anti-CLDN6 Recombinant Antibody (TAB-507LC) | Cyt, FC, FuncS | Mouse IgG |
| TAB-507LC-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (TAB-507LC-F(E)) | FC, IHC | Mouse Fab |
| TAB-508LC-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (TAB-508LC-F(E)) | FC, IHC | Mouse Fab |
| TAB-509LC-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (TAB-509LC-F(E)) | FC, IHC | Mouse Fab |
| TAB-510LC-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (TAB-510LC-F(E)) | FC, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0078-FY-S(P) | Mouse Anti-CLDN6 Recombinant Antibody; scFv Fragment (HPAB-0078-FY-S(P)) | Activ | Mouse scFv |
| HPAB-1496-FY-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (HPAB-1496-FY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-1497-FY-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (HPAB-1497-FY-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0078-FY-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (HPAB-0078-FY-F(E)) | Activ | Mouse Fab |
| HPAB-1496-FY-S(P) | Mouse Anti-CLDN6 Recombinant Antibody; scFv Fragment (HPAB-1496-FY-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-1497-FY-S(P) | Mouse Anti-CLDN6 Recombinant Antibody; scFv Fragment (HPAB-1497-FY-S(P)) | ELISA, FC | Mouse scFv |
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