Recombinant Anti-Clec7a Vesicular Antibody, EV Displayed (VS-0425-YC217)
CAT#: VS-0425-YC217
The Recombinant Anti-Clec7a Vesicular Antibody, EV Displayed (VS-0425-YC217) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to Clec7a-expressed cells or tissues. The Clec7a is a C-type lectin-like receptor, recognizing glucans from fungi and plants, playing a role in innate immune response. It resides in the natural killer gene complex region.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Group enriched (Karpas-707, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172243-CLEC7A
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- Clec7a
- Host Animal
- Rat
- Antibody Isotype
- IgG2a kappa
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- C-type lectin domain containing 7A
- Biological Process
- Immunity, Inflammatory response, Innate immunity
- Molecular Function
- Receptor
- Introduction
- This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
- Alternative Names
- CD369, CLECSF12, DECTIN-1, hDectin-1, SCARE2
- Gene ID
- 64581
- UniProt ID
- Q9BXN2
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Datasheet
MSDS
COA
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See other products for "CLEC7A"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-658-VHH | Recombinant Anti-Human CLEC7A VHH Single Domain Antibody | FUNC, FA, IP, ChiP | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2320z | Mouse Anti-CLEC7A Recombinant Antibody (clone 40A7) | FC, ICC, Neut | Mouse IgG2b |
| MOB-1600MZ | Recombinant Mouse Anti-Human CLEC7A Antibody (clone CE7) | FC | Mouse antibody |
| FN-157CQ | Mouse Anti-CLEC7A Recombinant Antibody (clone CBL-1320) | FuncS | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-187MZ | Rat Anti-Clec7a Recombinant Antibody (TAB-187MZ) | FC | Rat IgG2a, κ |
| TAB-188MZ | Rat Anti-Clec7a Recombinant Antibody (TAB-188MZ) | FC | Rat IgG1, κ |
| TAB-189MZ | Rat Anti-Clec7a Recombinant Antibody (TAB-189MZ) | FC | Rat IgG2a, κ |
| TAB-187MZ-F(E) | Rat Anti-Clec7a Recombinant Antibody; Fab Fragment (TAB-187MZ-F(E)) | FC | Rat Fab |
| TAB-188MZ-F(E) | Rat Anti-Clec7a Recombinant Antibody; Fab Fragment (TAB-188MZ-F(E)) | FC | Rat Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-475CQ | Mouse Anti-CLEC7A Recombinant Antibody (clone CBL360) | Block, FC, ICC, CyTOF® | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-477CQ | Rat Anti-CLEC7A Recombinant Antibody (clone CBL354) | Block, CyTOF®, FC | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4093 | Hi-Affi™ Rabbit Anti-CLEC7A Recombinant Antibody (clone SI163DS) | ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY85 | CytoStream™ Mouse Anti-CLEC7A Recombinant Antibody (VS-0225-XY85) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1504 | Anti-CLEC7A Immunohistochemistry Kit | IHC | |
| VS-0525-XY1505 | Anti-Mouse CLEC7A Immunohistochemistry Kit | IHC |
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