Recombinant Anti-Cr2 Vesicular Antibody, EV Displayed (VS-0425-YC751) (CAT#: VS-0425-YC751)
The Recombinant Anti-Cr2 Vesicular Antibody, EV Displayed (VS-0425-YC751) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to Cr2-expressed cells or tissues. Cr2 is a receptor for complement activation, influencing immune processes and associated with conditions like immunodeficiency and lupus.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52942/139626_A_8_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52942/139626_A_8_8.jpg
Figure 2 Tonsil
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52942/139626_A_4_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52942/139626_A_4_8.jpg
Figure 3 RNA cell line category: Cell line enhanced (Daudi, JURKAT, MOLT-4, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117322-CR2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117322-CR2
Figure 3 RNA cell line category: Cell line enhanced (Daudi, JURKAT, MOLT-4, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117322-CR2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117322-CR2
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- Cr2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Complement C3d receptor 2
- Biological Process
- Complement pathway, Host-virus interaction, Immunity, Innate immunity
- Molecular Function
- Host cell receptor for virus entry, Receptor
- Introduction
- Enables complement receptor activity. Acts upstream of or within with a negative effect on complement activation, alternative pathway. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; immunoglobulin mediated immune response; and skeletal system development. Located in external side of plasma membrane. Is expressed in several structures, including brain; hemolymphoid system; liver; placenta; and yolk sac. Human ortholog(s) of this gene implicated in common variable immunodeficiency 7; nasopharynx carcinoma; and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2).
- Alternative Names
- C3DR, CD21, CD35, Cr-1, Cr-2, Cr1
- Gene ID
- 12902
- UniProt ID
- A0A1B0GS59
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1139z | Mouse Anti-CR2 Recombinant Antibody (clone 19C8) | IHC, FC, ELISA | Mouse IgG2a |
| MRO-0289-CN | Rabbit Anti-CR2 Recombinant Antibody (clone CBACN-110) | WB, IF, IHC, IP, FC | Rabbit IgG |
| ZG-0622J | Rabbit Anti-CR2 Recombinant Antibody (clone 16F10) | ELISA, WB, IHC, IF, FC | Rabbit IgG |
| VS3-CJ755 | Mouse Anti-CR2 Recombinant Antibody (clone BU32) | IF, FC | Mouse IgG1 |
| VS3-CJ756 | Mouse Anti-CR2 Recombinant Antibody (clone ABT-CD21) | IHC-P | Mouse IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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