Recombinant Anti-Cr2 Vesicular Antibody, EV Displayed (VS-0425-YC751)
CAT#: VS-0425-YC751
The Recombinant Anti-Cr2 Vesicular Antibody, EV Displayed (VS-0425-YC751) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to Cr2-expressed cells or tissues. Cr2 is a receptor for complement activation, influencing immune processes and associated with conditions like immunodeficiency and lupus.
Gene Expression
Normal Tissue
Figure 1 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52942/139626_A_8_8.jpg
Normal Tissue
Figure 2 Tonsil
Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52942/139626_A_4_8.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (Daudi, JURKAT, MOLT-4, RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117322-CR2
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- Cr2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Complement C3d receptor 2
- Biological Process
- Complement pathway, Host-virus interaction, Immunity, Innate immunity
- Molecular Function
- Host cell receptor for virus entry, Receptor
- Introduction
- Enables complement receptor activity. Acts upstream of or within with a negative effect on complement activation, alternative pathway. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; immunoglobulin mediated immune response; and skeletal system development. Located in external side of plasma membrane. Is expressed in several structures, including brain; hemolymphoid system; liver; placenta; and yolk sac. Human ortholog(s) of this gene implicated in common variable immunodeficiency 7; nasopharynx carcinoma; and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2).
- Alternative Names
- C3DR, CD21, CD35, Cr-1, Cr-2, Cr1
- Gene ID
- 12902
- UniProt ID
- A0A1B0GS59
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Datasheet
MSDS
COA
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See other products for "CR2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-497CQ | Rabbit Anti-Cr2 Recombinant Antibody (clone 7G6) | WB, Neut, FC, IHC-Fr, IP, CyTOF® | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0795 | Hi-Affi™ Rabbit Anti-CR2 Recombinant Antibody (clone DS795AB) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3372 | PE-B*15:16/Human CR2 (VSYGSIVTY) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0109JF | Mouse Anti-Cr2 Recombinant Antibody (clone 4B2) | WB, ELISA, FC | Mouse IgG1, κ |
| VS3-CJ755 | Mouse Anti-CR2 Recombinant Antibody (clone BU32) | IF, FC | Mouse IgG1 |
| VS3-CJ756 | Mouse Anti-CR2 Recombinant Antibody (clone ABT-CD21) | IHC-P | Mouse IgG1, κ |
| VS3-CJ757 | Mouse Anti-CR2 Recombinant Antibody (clone PT0032) | IHC-P | Mouse IgG |
| VS3-CJ758 | Mouse Anti-CR2 Recombinant Antibody (VS3-CJ758) | WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0109JF-F(E) | Mouse Anti-Cr2 Recombinant Antibody (clone 4B2); Fab Fragment | FC, WB, ELISA, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0109JF-S(P) | Mouse Anti-Cr2 Recombinant Antibody (clone 4B2); scFv Fragment | FC, WB, ELISA, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC991 | AbPlus™ Anti-CR2 Magnetic Beads (VS-0724-YC991) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY89 | CytoStream™ Mouse Anti-CR2 Recombinant Antibody (VS-0225-XY89) | FC | Mouse IgG1, kappa |
| VS-0225-XY90 | CytoStream™ Mouse Anti-CR2 Recombinant Antibody (VS-0225-XY90) | FC | Mouse IgG1, kappa |
| VS13-YC243 | CytoStream™ Rabbit Anti-CR2 Recombinant Antibody (VS13-YC243) | WB, IF, IHC-P, FC, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1650 | Anti-CR2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1651 | Anti-Mouse CR2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1652 | Anti-Rat CR2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1653 | Anti-Monkey CR2 Immunohistochemistry Kit | IHC |
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