Recombinant Anti-Cr2 Vesicular Antibody, EV Displayed (VS-0425-YC751) (CAT#: VS-0425-YC751)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• Cr2

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Mouse

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Complement C3d receptor 2

• Biological Process
• Complement pathway, Host-virus interaction, Immunity, Innate immunity

• Molecular Function
• Host cell receptor for virus entry, Receptor

• Introduction
• Enables complement receptor activity. Acts upstream of or within with a negative effect on complement activation, alternative pathway. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; immunoglobulin mediated immune response; and skeletal system development. Located in external side of plasma membrane. Is expressed in several structures, including brain; hemolymphoid system; liver; placenta; and yolk sac. Human ortholog(s) of this gene implicated in common variable immunodeficiency 7; nasopharynx carcinoma; and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2).

• Alternative Names
• C3DR, CD21, CD35, Cr-1, Cr-2, Cr1

• Gene ID
• 12902

• UniProt ID
• A0A1B0GS59

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