Recombinant Anti-CYB5A Vesicular Antibody, EV Displayed (VS-0425-YC2)
CAT#: VS-0425-YC2
The Recombinant Anti-CYB5A Vesicular Antibody, EV Displayed (VS-0425-YC2) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CYB5A-expressed cells or tissues. Cytochrome B5 Type A (CYB5A) is a protein linked to Methemoglobinemia Type IV and Congenital Adrenal Hyperplasia due to 17-alpha-hydroxylase deficiency. This protein participates in metabolic pathways, with its functions including enzyme binding and cytochrome-c oxidase activity. CYB5B is identified as an important paralog of CYB5A.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to cytosol & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47548/1393_D4_4_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/58547/983_E12_2_selected.jpg
Normal Tissue
Figure 3 Testis
Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47548/138474_A_4_6.jpg
Normal Tissue
Figure 4 High expression in liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47548/138474_A_7_4.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, RT4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166347-CYB5A
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CYB5A
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Cytochrome b5 type A
- Biological Process
- Electron transport, Transport
- Cellular Localization
- Vesicles, Cytosol
- Introduction
- CYB5A (Cytochrome B5 Type A) is a Protein Coding gene. Diseases associated with CYB5A include Methemoglobinemia Type Iv and Adrenal Hyperplasia, Congenital, Due To 17-Alpha-Hydroxylase Deficiency. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. Gene Ontology (GO) annotations related to this gene include enzyme binding and cytochrome-c oxidase activity. An important paralog of this gene is CYB5B.
- Alternative Names
- CYB5
- Gene ID
- 1528
- UniProt ID
- P00167
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Datasheet
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "CYB5A"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3823z | Mouse Anti-CYB5A Recombinant Antibody (clone 15A6) | ELISA, IHC, IP, WB | Mouse IgG1, κ |
| MOB-0128CT | Recombinant Mouse anti-Human CYB5A Monoclonal antibody (47) | ELISA, WB | |
| VS-0923-FY46 | Recombinant Mouse Anti-CYB5A Antibody (VS-0923-FY46) | ELISA, WB, IHC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY596 | Anti-CYB5A Immunohistochemistry Kit | IHC | |
| VS-0525-XY1830 | Anti-Human CYB5A Immunohistochemistry Kit | IHC |
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