Recombinant Anti-CYB5A Vesicular Antibody, EV Displayed (VS-0425-YC2) (CAT#: VS-0425-YC2)
The Recombinant Anti-CYB5A Vesicular Antibody, EV Displayed (VS-0425-YC2) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CYB5A-expressed cells or tissues. Cytochrome B5 Type A (CYB5A) is a protein linked to Methemoglobinemia Type IV and Congenital Adrenal Hyperplasia due to 17-alpha-hydroxylase deficiency. This protein participates in metabolic pathways, with its functions including enzyme binding and cytochrome-c oxidase activity. CYB5B is identified as an important paralog of CYB5A.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47548/1393_D4_4_selected.jpg
(Immunofluorescent staining of human cell line RT4 shows localization to cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47548/1393_D4_4_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58547/983_E12_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58547/983_E12_2_selected.jpg
Figure 3 Testis
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47548/138474_A_4_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47548/138474_A_4_6.jpg
Figure 4 High expression in liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47548/138474_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47548/138474_A_7_4.jpg
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166347-CYB5A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166347-CYB5A
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CYB5A
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Cytochrome b5 type A
- Biological Process
- Electron transport, Transport
- Cellular Localization
- Vesicles, Cytosol
- Introduction
- CYB5A (Cytochrome B5 Type A) is a Protein Coding gene. Diseases associated with CYB5A include Methemoglobinemia Type Iv and Adrenal Hyperplasia, Congenital, Due To 17-Alpha-Hydroxylase Deficiency. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. Gene Ontology (GO) annotations related to this gene include enzyme binding and cytochrome-c oxidase activity. An important paralog of this gene is CYB5B.
- Alternative Names
- CYB5
- Gene ID
- 1528
- UniProt ID
- P00167
Downloads
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IgG Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3823z | Mouse Anti-CYB5A Recombinant Antibody (clone 15A6) | ELISA, IHC, IP, WB | Mouse IgG1, κ |
| MOB-0128CT | Recombinant Mouse anti-Human CYB5A Monoclonal antibody (47) | ELISA, WB | |
| VS-0923-FY46 | Recombinant Mouse Anti-CYB5A Antibody (VS-0923-FY46) | ELISA, WB, IHC | Mouse IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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