Recombinant Anti-EGF Vesicular Antibody, EV Displayed (VS-0425-YC621)
CAT#: VS-0425-YC621
The Recombinant Anti-EGF Vesicular Antibody, EV Displayed (VS-0425-YC621) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to EGF-expressed cells or tissues. EGF is a potent mitogenic factor part of the epidermal growth factor superfamily, crucial for cell growth and differentiation. Dysregulation links to cancer progression.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (EFO-21, SK-BR-3, U-251 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000138798-EGF
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- EGF
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Epidermal growth factor
- Molecular Function
- Growth factor
- Introduction
- This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
- Gene ID
- 1950
- UniProt ID
- P01133
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Related Diseases
Bladder Cancer
Non-small Cell Lung Cancer
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| HPAB-0157-WJ-S(P) | Mouse Anti-EGF Recombinant Antibody (clone 0914); scFv Fragment | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-718CQ | Mouse Anti-EGF Recombinant Antibody (clone CBL053) | Neut, WB, IHC | Mouse IgG1 |
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| NEUT-720CQ | Mouse Anti-Egf Recombinant Antibody (clone CBL628) | WB, Neut | Mouse IgG2b |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4151 | Hi-Affi™ Rabbit Anti-EGF Recombinant Antibody (clone SI226DS) | ELISA | Rabbit IgG |
| MOR-4152 | Hi-Affi™ Rabbit Anti-EGF Recombinant Antibody (clone SI227DS) | ELISA | Rabbit IgG |
| MOR-4153 | Hi-Affi™ Rabbit Anti-EGF Recombinant Antibody (clone SI228DS) | Neut | Rabbit IgG |
| MOR-4509 | Hi-Affi™ Rabbit Anti-EGF Recombinant Antibody (clone TH17DS) | ICC, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY176 | Mouse Anti-NHP EGF Recombinant Antibody (clone 10827) | ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2180 | Anti-EGF Immunohistochemistry Kit | IHC | |
| VS-0525-XY2181 | Anti-Mouse EGF Immunohistochemistry Kit | IHC |
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