Recombinant Mouse Anti-EPCAM Antibody (clone 1G8-8C7-10H8)
CAT#: VS3-FY505
This product is a recombinant mouse antibody that recognizes human EPCAM protein. The mAb was purified by affinity chromatography.
Gene Expression
Tested Data
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67463/1592_H11_2_selected.jpg
Normal Tissue
Figure 2 Thyroid gland
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_B_2_5.jpg
Normal Tissue
Figure 3 Colon
Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_8_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000119888-EPCAM
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IHC
Figure 1. Recombinant Mouse Anti-EPCAM Antibody (clone 1G8-8C7-10H8) in IHC.
Immunohistochemical analysis of paraffin-embedded colon carcinoma using EpCAM antibody. High pressure and high temperature sodium citrate pH 6.0 for antigen retrieval.
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Specifications
- Immunogen
- Synthesized peptide derived from human Ep-CAM
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human EPCAM
- Species Reactivity
- Human
- Clone
- 1G8-8C7-10H8
- Applications
- Immunohistochemistry-Paraffin
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity Chromatography Purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- PBS pH 7.3, 50% Glycerol, 0.5% BSA
- Preservative
- 0.02% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry: 1/100-1/500
Target
- Alternative Names
- Epithelial Cell Adhesion Molecule; Tumor-Associated Calcium Signal Transducer 1; Major Gastrointestinal Tumor-Associated Protein GA733-2; Adenocarcinoma-Associated Antigen; Cell Surface Glycoprotein Trop-1; Epithelial Glycoprotein 314; TACSTD1; EGP314; MIC18; TROP1; M4S1; KSA; Membrane Component, Chromosome 4, Surface Marker (35kD Glycoprotein); Antigen Identified By Monoclonal Antibody AUA1; Human Epithelial Glycoprotein-2; Epithelial Cell Surface Antigen
- Gene ID
- 4072
- UniProt ID
- P16422
- Sequence Similarities
- Belongs to the EPCAM family.
- Cellular Localization
- Cell junction, Cell membrane, Membrane, Tight junction
- Post Translation Modifications
- Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability.
- Protein Refseq
- NP_002345.2
- Function
- May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L013E | anti-EPCAM immunotoxin MOC31 (IgG)-PE | Cytotoxicity assay, Functional assay | |
| AGTO-L013D | anti-EPCAM immunotoxin MOC31 (IgG)-DT | Cytotoxicity assay, Functional assay | |
| AGTO-L013G | anti-EPCAM immunotoxin MOC31 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
| AGTO-L013R | anti-EPCAM immunotoxin MOC31 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0531CL-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (HE2) | ELISA, Inhib | |
| TAB-363MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-363MZ) | ELISA, FuncS | Mouse IgG1, κ |
| TAB-364MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-364MZ) | FC | Mouse IgG1 |
| TAB-365MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-365MZ) | FC | Mouse IgG1 |
| TAB-366MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-366MZ) | ELISA, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-356MZ | Anti-Human EPCAM Recombinant Antibody (3-171) | Cyt, ELISA, FC, WB | Human antibody |
| TAB-357MZ | Anti-Human EPCAM Recombinant Antibody (7-F17) | ELISA | Human antibody |
| TAB-358MZ | Anti-Human EPCAM Recombinant Antibody (12-C15) | ELISA | Human antibody |
| TAB-359MZ | Anti-Human EPCAM Recombinant Antibody (16-G5) | ELISA | Human antibody |
| TAB-360MZ | Anti-Human EPCAM Recombinant Antibody (17-C20) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1163 | Hi-Affi™ Rabbit Anti-EPCAM Recombinant Antibody (clone DS1163AB) | IHC-P, WB, ICC, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0095-YC-F(E) | Mouse Anti-EPCAM Recombinant Antibody (clone MOC31); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0129CQ-F(E) | Human Anti-EPCAM Recombinant Antibody (clone 17-1A); Fab Fragment | ELISA, IHC, FC | Chimeric (mouse/human) Fab |
| FAMAB-0130CQ-F(E) | Human Anti-EPCAM Recombinant Antibody (clone 323/A3); Fab Fragment | ELISA, IHC, FC | Chimeric (mouse/human) Fab |
| FAMAB-0131CQ-F(E) | Mouse Anti-EPCAM Recombinant Antibody (clone MOC-161); Fab Fragment | ELISA, IHC, FC | Mouse Fab |
| HPAB-2216LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2216LY-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0129CQ-S(P) | Mouse Anti-EPCAM Recombinant Antibody (clone 17-1A); scFv Fragment | ELISA, IHC, FC | Mouse scFv |
| FAMAB-0130CQ-S(P) | Mouse Anti-EPCAM Recombinant Antibody (clone 323/A3); scFv Fragment | ELISA, IHC, FC | Mouse scFv |
| FAMAB-0131CQ-S(P) | Mouse Anti-EPCAM Recombinant Antibody (clone MOC-161); scFv Fragment | ELISA, IHC, FC | Mouse scFv |
| HPAB-2218LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2218LY-S(P)) | ELISA | Human scFv |
| HPAB-2219LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2219LY-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0538-CN | Mouse Anti-EPCAM Recombinant Antibody (clone 3-E1-E2) | WB, IF, IHC, FC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-106 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-106) | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
| AFC-TAB-213 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-213) | Neut, ELISA, IF, IP, FuncS | ADCC enhanced antibody |
| AFC-TAB-701 | Afuco™ Anti-EpCAM ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-701) | ELISA, IP, FC, FuncS, IF, Neut | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2240LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2240LY) | ELISA | Human IgG |
| HPAB-1520-FY | Mouse Anti-EPCAM Recombinant Antibody (clone 2A9) | ELISA, FC | Mouse IgG |
| HPAB-1521-FY | Mouse Anti-EPCAM Recombinant Antibody (clone FMU-EPCAM-4E4) | ELISA, FC | Mouse IgG |
| HPAB-1522-FY | Mouse Anti-EPCAM Recombinant Antibody (HPAB-1522-FY) | ELISA, FC | Mouse IgG |
| HPAB-2050-FY | Human Anti-CD46 Recombinant Antibody (clone K53) | FC | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0031 | APC-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM | |
| MHC-CN0032 | PE-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1517 | AbPlus™ Anti-EPCAM Magnetic Beads (VS-0724-YC1517) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC37 | Mouse Anti-EPCAM Recombinant Antibody (VS-0924-YC37) - Cancer Stem Cell Marker | IHC, WB | Mouse IgG1 |
| VS-0924-YC38 | Rabbit Anti-EPCAM Antibody (VS-0924-YC38) - Cancer Stem Cell Marker | IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY18 | Human Anti-EpCAM (clone 3-171) scFv-Fc Chimera | Cyt, ELISA, FC, WB | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY773 | Anti-EPCAM Immunohistochemistry Kit | IHC | |
| VS-0525-XY2307 | Anti-Human EPCAM Immunohistochemistry Kit | IHC | |
| VS-0525-XY2308 | Anti-Mouse EPCAM Immunohistochemistry Kit | IHC | |
| VS-0525-XY2309 | Anti-Canine EPCAM Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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