Recombinant Anti-FCER1G Vesicular Antibody, EV Displayed (VS-0425-YC724)

CAT#: VS-0425-YC724

The Recombinant Anti-FCER1G Vesicular Antibody, EV Displayed (VS-0425-YC724) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FCER1G-expressed cells or tissues. FCER1G is a gamma chain essential for high-affinity IgE receptor functioning in allergic reactions, also part of other Fc receptor subunits.

Gene Expression
Figure 1 IHC staining of human bone marrow Figure 2 Cerebral cortex Figure 3 Colon Figure 4 Liver Figure 5 Lymph node Figure 6 Spleen Figure 7 RNA cell line category: Group enriched (HEL, HMC-1, THP-1, U-266/84, U-937)

Recombinant Antibody

  • Application
  • Block, ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • FCER1G
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Fc epsilon receptor Ig
  • Biological Process
  • Immunity, Innate immunity
  • Molecular Function
  • IgE-binding protein, Receptor
  • Introduction
  • The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors.
  • Alternative Names
  • FcepsilonRIgamma
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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