Recombinant Anti-FZD5 Vesicular Antibody, EV Displayed (VS-0425-YC416) (CAT#: VS-0425-YC416)
The Recombinant Anti-FZD5 Vesicular Antibody, EV Displayed (VS-0425-YC416) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FZD5-expressed cells or tissues. The FZD5 is a receptor for Wnt signaling proteins, interacting with the ligand Wnt5A.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human caudate
(Immunohistochemical staining of human caudate shows moderate positivity in neurons.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/ihc_selected.jpg
(Immunohistochemical staining of human caudate shows moderate positivity in neurons.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_B_7_5.jpg
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_B_7_5.jpg
Figure 3 Pancreas
(Exocrine glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_A_2_3.jpg
(Exocrine glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_A_2_3.jpg
Figure 4 Testis
(Elongated or late spermatids Staining: Low Intensity: Moderate Quantity: <25% Pachytene spermatocytes Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_A_6_6.jpg
(Elongated or late spermatids Staining: Low Intensity: Moderate Quantity: <25% Pachytene spermatocytes Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_A_6_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (BEWO, CACO-2, Hep G2, NTERA-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163251-FZD5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163251-FZD5
Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- FZD5
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Frizzled class receptor 5
- Biological Process
- Wnt signaling pathway
- Molecular Function
- Developmental protein, G-protein coupled receptor, Receptor, Transducer
- Introduction
- Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
- Alternative Names
- C2orf31, DKFZP434E2135, HFZ5
- Gene ID
- 7855
- UniProt ID
- Q13467
Downloads
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IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0749CT | Recombinant Mouse anti-Human FZD5 Monoclonal antibody (EML2242) | WB | |
| MRO-1876-CN | Rabbit Anti-FZD5 Polyclonal Antibody (MRO-1876-CN) | WB | Rabbit IgG |
| PABJ-0145 | Human Anti-FZD5 Recombinant Antibody (PABJ-0145) | ELISA, Inhib, FuncS | Human IgG |
| VS3-QX453 | Mouse Anti-FZD5 Recombinant Antibody (clone 2D12) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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