Recombinant Anti-FZD5 Vesicular Antibody, EV Displayed (VS-0425-YC416)
CAT#: VS-0425-YC416
The Recombinant Anti-FZD5 Vesicular Antibody, EV Displayed (VS-0425-YC416) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FZD5-expressed cells or tissues. The FZD5 is a receptor for Wnt signaling proteins, interacting with the ligand Wnt5A.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human caudate
Immunohistochemical staining of human caudate shows moderate positivity in neurons.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_B_7_5.jpg
Normal Tissue
Figure 3 Pancreas
Exocrine glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_A_2_3.jpg
Normal Tissue
Figure 4 Testis
Elongated or late spermatids Staining: Low Intensity: Moderate Quantity: <25% Pachytene spermatocytes Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (BEWO, CACO-2, Hep G2, NTERA-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163251-FZD5
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Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- FZD5
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Frizzled class receptor 5
- Biological Process
- Wnt signaling pathway
- Molecular Function
- Developmental protein, G-protein coupled receptor, Receptor, Transducer
- Introduction
- Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
- Alternative Names
- C2orf31, DKFZP434E2135, HFZ5
- Gene ID
- 7855
- UniProt ID
- Q13467
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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|---|---|---|---|
| MOB-0749CT | Recombinant Mouse anti-Human FZD5 Monoclonal antibody (EML2242) | WB | |
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| VS3-QX453 | Mouse Anti-FZD5 Recombinant Antibody (clone 2D12) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABJ-0145-S(P) | Human Anti-FZD5 Recombinant Antibody scFv Fragment (PABJ-0145-S(P)) | ELISA, Inhib, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABJ-0145-F(E) | Human Anti-FZD5 Recombinant Antibody Fab Fragment (PABJ-0145-F(E)) | ELISA, Inhib, FuncS | Human Fab |
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