Recombinant Anti-GRIN1 Vesicular Antibody, EV Displayed (VS-0425-YC673)
CAT#: VS-0425-YC673
The Recombinant Anti-GRIN1 Vesicular Antibody, EV Displayed (VS-0425-YC673) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to GRIN1-expressed cells or tissues. GRIN1 is a critical subunit of N-methyl-D-aspartate receptors, which are essential for synaptic plasticity and involved in memory and learning.
Gene Expression
Normal Tissue
Figure 1 High expression in hippocampal formation
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67773/168000_B_9_6_selected.jpg
Normal Tissue
Figure 2 Low expression in tonsil
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67773/168000_A_4_8_val_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67773/168000_B_8_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67773/168000_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (OE19, REH, RPMI-8226, SCLC-21H, SH-SY5Y, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000176884-GRIN1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- GRIN1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Glutamate ionotropic receptor NMDA type subunit 1
- Biological Process
- Ion transport, Transport
- Molecular Function
- Ion channel, Ligand-gated ion channel, Receptor
- Introduction
- The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
- Alternative Names
- GluN1, NMDAR1
- Gene ID
- 2902
- UniProt ID
- Q05586
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC673. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "GRIN1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2471CT | Recombinant Mouse anti-Human GRIN1 Monoclonal antibody (7D6) | WB, IP, ICC, IF | |
| HPAB-0025-CN | Human Anti-GRIN1 Recombinant Antibody (HPAB-0025-CN) | ELISA, ICC, FC | Human IgG |
| HPAB-0026-CN | Human Anti-GRIN1 Recombinant Antibody (HPAB-0026-CN) | ELISA, ICC, FC | Human IgG |
| HPAB-0027-CN | Human Anti-GRIN1 Recombinant Antibody (HPAB-0027-CN) | ELISA, ICC, FC | Human IgG |
| VS3-FY616 | Recombinant Rabbit Anti-GRIN1 Antibody (clone R08-4B6) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1510 | Rabbit Anti-GRIN1 Recombinant Antibody (clone DS1510AB) | WB, IP, IHC-P, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0025-CN-S(P) | Human Anti-GRIN1 Recombinant Antibody; scFv Fragment (HPAB-0025-CN-S(P)) | ELISA, ICC, FC | Human scFv |
| HPAB-0026-CN-S(P) | Human Anti-GRIN1 Recombinant Antibody; scFv Fragment (HPAB-0026-CN-S(P)) | ELISA, ICC, FC | Human scFv |
| HPAB-0027-CN-S(P) | Human Anti-GRIN1 Recombinant Antibody; scFv Fragment (HPAB-0027-CN-S(P)) | ELISA, ICC, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0025-CN-F(E) | Human Anti-GRIN1 Recombinant Antibody; Fab Fragment (HPAB-0025-CN-F(E)) | ELISA, ICC, FC | Human Fab |
| HPAB-0026-CN-F(E) | Human Anti-GRIN1 Recombinant Antibody; Fab Fragment (HPAB-0026-CN-F(E)) | ELISA, ICC, FC | Human Fab |
| HPAB-0027-CN-F(E) | Human Anti-GRIN1 Recombinant Antibody; Fab Fragment (HPAB-0027-CN-F(E)) | ELISA, ICC, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC470 | CytoStream™ Rabbit Anti-GRIN1 Recombinant Antibody (VS13-YC470) | WB, ICC, IF, IHC-P, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2919 | Anti-Mouse GRIN1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2920 | Anti-Rat GRIN1 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: Inhib, Cyt
Application: FuncS, IF, Neut, ELISA, FC, IP, WB
Application: ELISA, IHC, FC, WB, IF, IA
Application: Neut, ELISA, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, Neut
Application: ELISA, Neut
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
