Recombinant Anti-HHLA2 Vesicular Antibody, EV Displayed (VS-0425-YC175)

CAT#: VS-0425-YC175

The Recombinant Anti-HHLA2 Vesicular Antibody, EV Displayed (VS-0425-YC175) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to HHLA2-expressed cells or tissues. The HHLA2 is a protein ligand regulating cell-mediated immunity by inhibiting T lymphocyte proliferation.

Gene Expression
Figure 1 Cerebral cortex Figure 2 RNA cell line category: Cell line enhanced (CACO-2, HDLM-2, Karpas-707)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • HHLA2
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • HERV-H LTR-associating 2
  • Introduction
  • This gene encodes a protein ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  • Alternative Names
  • B7-H5, B7-H7, B7H7, B7y
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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