Recombinant Anti-ICOS Vesicular Antibody, EV Displayed (VS-0425-YC522)
CAT#: VS-0425-YC522
The Recombinant Anti-ICOS Vesicular Antibody, EV Displayed (VS-0425-YC522) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ICOS-expressed cells or tissues. ICOS belongs to the CD28 and CTLA-4 receptor family and forms homodimers involved in cell signaling and immune response regulation. The protein plays a significant role in the proliferation of immune cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1813_D4_33_selected.jpg
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ICOS
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Inducible T cell costimulator
- Cellular Localization
- Plasma membrane, Actin filaments
- Introduction
- The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
- Alternative Names
- AILIM, CD278
- Gene ID
- 29851
- UniProt ID
- Q9Y6W8
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC522. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Related Diseases
Primary Immunodeficiency
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ICOS"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1124z | Mouse Anti-ICOS Recombinant Antibody (clone 41C5) | FC, IHC, IP, FuncS | Mouse IgG1, κ |
| FN-184CQ | Hamster Anti-ICOS Recombinant Antibody (clone C398.4A) | FC, FuncS | Hamster IgG |
| FN-225CQ | Mouse Anti-ICOS Recombinant Antibody (clone ISA-3) | FC, FuncS, TCA | Mouse IgG1, κ |
| HPAB-1261WJ | Human Anti-ICOS Recombinant Antibody (HPAB-1261WJ) | Neut, ELISA | Human IgG |
| HPAB-1262WJ | Human Anti-ICOS Recombinant Antibody (HPAB-1262WJ) | Neut, ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-128CT | Mouse Anti-ICOS Recombinant Antibody (TAB-128CT) | ELISA, WB | Mouse IgG |
| TAB-128CT-S(P) | Mouse Anti-ICOS Recombinant Antibody; scFv Fragment (TAB-128CT-S(P)) | ELISA, WB | Mouse scFv |
| TAB-128CT-F(E) | Mouse Anti-ICOS Recombinant Antibody; Fab Fragment (TAB-128CT-F(E)) | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-129CT | Human Anti-ICOS Recombinant Antibody (TAB-129CT) | ELISA, Neut | Human IgG2, κ |
| TAB-129CT-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (TAB-129CT-S(P)) | ELISA, Neut | Human scFv |
| TAB-129CT-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (TAB-129CT-F(E)) | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-941CQ | Mouse Anti-ICOS Recombinant Antibody (clone CBL817) | Neut, FC, CyTOF | Mouse IgG1 |
| NEUT-942CQ | Rat Anti-Icos Recombinant Antibody (clone 7E.17G9) | FC, FuncS, Neut | Rat IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-943CQ | Rat Anti-Icos Recombinant Antibody (NEUT-943CQ) | Block, FC | Rat IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1727 | Rabbit Anti-ICOS Recombinant Antibody (clone DS1727AB) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0109-CN-S(P) | Hamster Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0109-CN-S(P)) | ELISA, FC, IHC | Hamster scFv |
| HPAB-0110-CN-S(P) | Hamster Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0110-CN-S(P)) | ELISA, FC, IHC | Hamster scFv |
| HPAB-0111-CN-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0111-CN-S(P)) | ELISA, FC, IHC | Humanized scFv |
| HPAB-1261WJ-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-1261WJ-S(P)) | Neut, ELISA | Human scFv |
| HPAB-1262WJ-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-1262WJ-S(P)) | Neut, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0073-WJ-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0073-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0022LY-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0022LY-F(E)) | WB | Human Fab |
| HPAB-0052-YJ-F(E) | Human Anti-ICOS Recombinant Antibody (clone JMab-136); Fab Fragment | ELISA | Human Fab |
| HPAB-1261WJ-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-1261WJ-F(E)) | Neut, ELISA | Human Fab |
| HPAB-1262WJ-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-1262WJ-F(E)) | Neut, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1522 | Human Anti-ICOS Recombinant Antibody (clone JTX-2011) | ELISA, FC | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY123 | CytoStream™ Mouse Anti-ICOS Recombinant Antibody (VS-0225-XY123) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY63 | Human Anti-ICOS (clone JMab-136) scFv-Fc Chimera | ELISA, FC | Human IgG2, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3374 | Anti-ICOS Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, IHC-Fr, IHC-P, ICC, IF
Application: ELISA, WB, IF, FC, IP
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: WB, Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, WB, BLI, SPR
Application: ELISA, FC, WB, FuncS
Application: Neut, FC
Application: WB, ELISA, FC, IHC, IF, IP
Application: ELISA, WB, IF, FC, IP
Application: WB, IHC-Fr, IHC-P, ICC, IF
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: WB, Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, WB, BLI, SPR
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
