Recombinant Anti-IL2RB Vesicular Antibody, EV Displayed (VS-0425-YC518)
CAT#: VS-0425-YC518
The Recombinant Anti-IL2RB Vesicular Antibody, EV Displayed (VS-0425-YC518) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to IL2RB-expressed cells or tissues. IL2RB is a beta subunit of the interleukin 2 receptor, crucial in T cell-mediated immune responses. This subunit forms part of the receptor complexes that bind interleukin 2, with the beta/gamma subunit heterotrimer being the high-affinity form. It is primarily expressed in the hematopoietic system, with certain variants showing placenta-specific expression due to alternative promoter usage.
Gene Expression
Normal Tissue
Figure 1 Bone marrow
Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62657/139408_B_5_4.jpg
Normal Tissue
Figure 2 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62657/139408_A_8_8.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100385-IL2RB
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- IL2RB
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Interleukin 2 receptor subunit beta
- Biological Process
- Host-virus interaction
- Molecular Function
- Receptor
- Introduction
- The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression. [provided by RefSeq, Sep 2016]
- Alternative Names
- CD122, IL15RB
- Gene ID
- 3560
- UniProt ID
- P14784
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC518. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "IL2RB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1173z | Mouse Anti-IL2RB Recombinant Antibody (clone 40D9) | FC, IP, FuncS | Mouse IgG1 |
| MOB-1587MZ | Recombinant Mouse Anti-Human IL2RB Antibody (clone 38403.2) | ELISA, Neut, WB | Mouse antibody |
| FN-027CQ | Mouse Anti-IL2RB Recombinant Antibody (clone 9A2) | FC, FuncS | Mouse IgG2a, κ |
| FAMAB-1403CQ | Rabbit Anti-IL2RB Recombinant Antibody (clone 5H4) | FC | Rabbit IgG |
| HPAB-2114-FY | Mouse Anti-IL2RB Recombinant Antibody (clone MAKA41) | Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-637LC | Mouse Anti-IL2RB Recombinant Antibody (TAB-637LC) | ELISA, FC, FuncS | Mouse IgG1, κ |
| TAB-637LC-S(P) | Mouse Anti-IL2RB Recombinant Antibody; scFv Fragment (TAB-637LC-S(P)) | ELISA, FC | Mouse scFv |
| TAB-638LC-S(P) | Mouse Anti-IL2RB Recombinant Antibody; scFv Fragment (TAB-638LC-S(P)) | ELISA, FC | Mouse scFv |
| TAB-637LC-F(E) | Mouse Anti-IL2RB Recombinant Antibody; Fab Fragment (TAB-637LC-F(E)) | ELISA, FC | Mouse Fab |
| TAB-638LC-F(E) | Mouse Anti-IL2RB Recombinant Antibody; Fab Fragment (TAB-638LC-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-639LC | Human Anti-IL2RB Recombinant Antibody (TAB-639LC) | ELISA, FC, FuncS | Humanized antibody |
| TAB-639LC-S(P) | Human Anti-IL2RB Recombinant Antibody; scFv Fragment (TAB-639LC-S(P)) | ELISA, FC | Humanized scFv |
| TAB-640LC-S(P) | Human Anti-IL2RB Recombinant Antibody; scFv Fragment (TAB-640LC-S(P)) | ELISA, FC | Humanized scFv |
| TAB-639LC-F(E) | Human Anti-IL2RB Recombinant Antibody; Fab Fragment (TAB-639LC-F(E)) | ELISA, FC | Humanized Fab |
| TAB-640LC-F(E) | Human Anti-IL2RB Recombinant Antibody; Fab Fragment (TAB-640LC-F(E)) | ELISA, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1362CQ | Mouse Anti-IL2RB Recombinant Antibody (clone CBL444) | FC, IHC, CyTOF, Neut | Mouse IgG1 |
| NEUT-1363CQ | Mouse Anti-IL2RB Recombinant Antibody (clone 1Y60) | IHC, Neut, WB | Mouse IgG1 |
| NEUT-1364CQ | Mouse Anti-IL2RB Recombinant Antibody (clone CBL079) | Neut, IHC | Mouse IgG1 |
| NEUT-1365CQ | Rat Anti-Il2rb Recombinant Antibody (clone TM-b1) | IP, FC, Neut | Rat IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1366CQ | Rat Anti-Il2rb Recombinant Antibody (NEUT-1366CQ) | Block, FC, IP | Rat IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0249CQ-F(E) | Mouse Anti-IL2RB Recombinant Antibody (clone MIK-BETA 1); Fab Fragment | FC | Mouse Fab |
| HPAB-2114-FY-F(E) | Mouse Anti-IL2RB Recombinant Antibody (clone MAKA41); Fab Fragment | Inhib | Mouse Fab |
| HPAB-1561WJ-F(E) | Human Anti-IL2RB Recombinant Antibody; Fab Fragment (clone A23A41) | ELISA, WB, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2114-FY-S(P) | Mouse Anti-IL2RB Recombinant Antibody (clone MAKA41); scFv Fragment | Inhib | Mouse scFv |
| HPAB-1561WJ-S(P) | Human Anti-IL2RB Recombinant Antibody; scFv Fragment (clone A23A41) | ELISA, WB, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY115 | Mouse Anti-IL2RB (clone A41) scFv-Fc Chimera | Inhib | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3523 | Anti-IL2RB Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
-2.png)
Application: WB, ELISA
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, Inhib, FuncS
Application: ELISA
Application: ELISA, Neut
Application: ELISA, Activ, Block
Application: ELISA, WB
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
