Recombinant Rabbit Anti-IL7 Capture Antibody (clone R08-5R8)
CAT#: VS3-WK1738
This antibody is a rabbit recombinant antibody against human IL7. It was developed by immunization of rabbit with recombinant human IL7 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. The sandwich ELISA was established using matched antibody pair R08-5R8 and R03-5G2. The clone R08-5R8 can be used as a capture antibody in ELISA analysis to identify human IL7.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human stomach, upper
Immunohistochemical staining of human stomach, upper shows strong cytoplasmic and membranous positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (CAPAN-2, HDLM-2, HEL, HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104432-IL7
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Specifications
- Immunogen
- Recombinant human IL7 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human IL7
- Species Reactivity
- Human
- Clone
- R08-5R8
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Interleukin 7
- Gene ID
- 3574
- UniProt ID
- P13232
- Long Name
- Interleukin 7
- Sequence Similarities
- Belongs to the IL-7/IL-9 family.
- Cellular Localization
- Secreted
- Protein Refseq
- NP_000871.1
- Function
- Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis. Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Detection antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
Secondary Antibody
See other products for "IL7"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1626z | Mouse Anti-IL7 Recombinant Antibody (clone 27C6) | ELISA, WB, FuncS | Mouse IgG1 |
| MOB-2117MZ | Recombinant Mouse Anti-Human IL7 Antibody (clone 8528.222) | ELISA, Neut, WB | Mouse antibody |
| VS3-QX602 | Mouse Anti-IL7 Recombinant Antibody (clone AH34-12) | ELISA, WB, ICC, IHC | Mouse IgG1 |
| VS3-QX603 | Mouse Anti-IL7 Recombinant Antibody (clone AH31-34) | ELISA, WB, ICC, IHC | Mouse IgG1 |
| VS3-WK1739 | Recombinant Rabbit Anti-IL7 Detection Antibody (clone R03-5G2) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1503CQ | Mouse Anti-IL7 Recombinant Antibody (clone CBL114) | Neut, WB, IHC | Mouse IgG1 |
| NEUT-1504CQ | Mouse Anti-IL7 Recombinant Antibody (clone CBL274) | Neut, ELISA | Mouse IgG1 |
| NEUT-1505CQ | Mouse Anti-IL7 Recombinant Antibody (clone CBL415) | WB, ELISA, Neut | Mouse IgG1 |
| NEUT-1506CQ | Mouse Anti-IL7 Recombinant Antibody (clone MM0410-12T6) | WB, Neut, IHC, IHC-P | Mouse IgG1 |
| NEUT-1507CQ | Mouse Anti-IL7 Recombinant Antibody (clone NYR-hi7) | WB, ELISA, Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1510CQ | Mouse Anti-Il7 Recombinant Antibody (clone M25) | Block | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1815 | Rabbit Anti-IL7 Recombinant Antibody (clone DS1815AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY153 | AbPlus™ Anti-IL7 Magnetic Beads (CBL889) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3542 | Anti-IL7 Immunohistochemistry Kit | IHC |
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