Recombinant Anti-ITGAX Vesicular Antibody, EV Displayed (VS-0425-YC235)
CAT#: VS-0425-YC235
The Recombinant Anti-ITGAX Vesicular Antibody, EV Displayed (VS-0425-YC235) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ITGAX-expressed cells or tissues. The ITGAX protein enables integrin binding activity and is involved in gene expression regulation. It is expressed in the heart and hemolymphoid system.
Gene Expression
Normal Tissue
Figure 1 High expression in spleen
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4723/14046_B_7_4_selected.jpg
Normal Tissue
Figure 2 Low expression in cerebral cortex
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4723/14046_B_9_5_val_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4458/14042_B_7_5.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4458/14042_A_7_8.jpg
Normal Tissue
Figure 5 Spleen
Cells in red pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in white pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4458/14042_B_8_4.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enriched (HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140678-ITGAX
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ITGAX
- Host Animal
- Hamster
- Antibody Isotype
- IgG1 kappa
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein G
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Integrin subunit alpha X
- Biological Process
- Cell adhesion
- Molecular Function
- Integrin, Receptor
- Cellular Localization
- Vesicles, Plasma membrane
- Introduction
- Predicted to enable integrin binding activity and receptor tyrosine kinase binding activity. Involved in positive regulation of gene expression and positive regulation of myelination. Acts upstream of or within defense response to virus. Located in external side of plasma membrane. Is expressed in heart and hemolymphoid system. Orthologous to human ITGAX (integrin subunit alpha X).
- Alternative Names
- Cd11c, Cr4, N418
- Gene ID
- 16411
- UniProt ID
- Q9QXH4
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Datasheet
MSDS
COA
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See other products for "ITGAX"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3769z | Mouse Anti-ITGAX Recombinant Antibody (clone 20F12) | WB, ELISA, FC | Mouse IgG1 |
| VS-0522-LC244 | Rat Anti-Itgax Recombinant Antibody (VS-0522-LC244) | IP, FC, IHC | Rat IgG2b |
| VS-0522-LC245 | Rabbit Anti-Itgax Recombinant Antibody (VS-0522-LC245) | IP, FC, IHC | Rabbit IgG |
| VS3-XY921 | Mouse Anti-ITGAX Recombinant Antibody (clone 4ALM2/1.6.11) | FC, IF | Mouse IgG1 |
| VS3-XY3401 | Rabbit Anti-ITGAX Recombinant Antibody (clone R06-5A7) | WB, IHC-P, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1580CL | Hamster Anti-ITGAX Recombinant Antibody (TAB-1580CL) | FC | Hamster IgG1, κ |
| TAB-1580CL-S(P) | Hamster Anti-ITGAX Recombinant Antibody; scFv Fragment (TAB-1580CL-S(P)) | FC | Hamster scFv |
| TAB-1580CL-F(E) | Hamster Anti-ITGAX Recombinant Antibody; Fab Fragment (TAB-1580CL-F(E)) | FC | Hamster Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0297MZ | Chicken Anti-ITGAX Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1584CQ | Recombinant Mouse Anti-ITGAX Antibody (3.9) | FC, CyTOF, BL, IHC | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1881 | Hi-Affi™ Recombinant Rabbit Anti-ITGAX Monoclonal Antibody (DS1881AB) | ICC, IHC-P, IHC-P, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0304-CN-S(P) | Hamster Anti-ITGAX Recombinant Antibody (clone N418); scFv Fragment | WB, ELISA, IHC | Hamster scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0304-CN-F(E) | Hamster Anti-ITGAX Recombinant Antibody (clone N418); Fab Fragment | WB, ELISA, IHC | Hamster Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY74 | Mouse Anti-NHP ITGAX Recombinant Antibody (clone BU15) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY151 | CytoStream™ Armenian Hamster Anti-ITGAX Recombinant Antibody (VS-0225-XY151) | FC | Armenian Hamster IgG1 |
| VS13-YC601 | CytoStream™ Hamster Anti-Itgax Recombinant Antibody (VS13-YC601) | FC | Armenian hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3647 | Anti-ITGAX Immunohistochemistry Kit | IHC | |
| VS-0525-XY3648 | Anti-Mouse ITGAX Immunohistochemistry Kit | IHC | |
| VS-0525-XY3650 | Anti-Human ITGAX Immunohistochemistry Kit | IHC |
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