Recombinant Anti-ITGB8 Vesicular Antibody, EV Displayed (VS-0425-YC569)
CAT#: VS-0425-YC569
The Recombinant Anti-ITGB8 Vesicular Antibody, EV Displayed (VS-0425-YC569) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ITGB8-expressed cells or tissues. ITGB8 is an integrin beta chain involved in cell-extracellular matrix interaction, particularly in airway epithelium.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27796/231_A10_2_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27797/165151_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27797/165151_A_7_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27797/165151_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27797/165151_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27797/165151_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (AF22, EFO-21, RPTEC TERT1, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105855-ITGB8
❮
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ITGB8
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Integrin subunit beta 8
- Biological Process
- Cell adhesion
- Molecular Function
- Integrin, Receptor
- Cellular Localization
- Plasma membrane, Cytosol
- Introduction
- This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
- Gene ID
- 3696
- UniProt ID
- P26012
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ITGB8"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2027MZ | Recombinant Mouse Anti-Human ITGB8 Antibody | WB | Mouse antibody |
| HPAB-0400-WJ | Mouse Anti-ITGB8 Recombinant Antibody (HPAB-0400-WJ) | ELISA | Mouse IgG |
| HPAB-0401-WJ | Mouse Anti-ITGB8 Recombinant Antibody (HPAB-0401-WJ) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0303MZ | Chicken Anti-ITGB8 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0400-WJ-S(P) | Mouse Anti-ITGB8 Recombinant Antibody; scFv Fragment (HPAB-0400-WJ-S(P)) | ELISA | Mouse scFv |
| HPAB-0401-WJ-S(P) | Mouse Anti-ITGB8 Recombinant Antibody; scFv Fragment (HPAB-0401-WJ-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0400-WJ-F(E) | Mouse Anti-ITGB8 Recombinant Antibody; Fab Fragment (HPAB-0400-WJ-F(E)) | ELISA | Mouse Fab |
| HPAB-0401-WJ-F(E) | Mouse Anti-ITGB8 Recombinant Antibody; Fab Fragment (HPAB-0401-WJ-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0917 | PE-A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer | FCM, IHC | |
| MHC-CN0918 | APC-A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer | FCM, IHC | |
| MHC-CN0919 | FITC-A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer | FCM, IHC | |
| MHC-CN0920 | A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC230 | SmartAb™ Recombinant Anti-ITGB8 pH-dependent Antibody (VS-0825-YC230) | ELISA | Mouse IgG |
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