Recombinant Anti-KCNK4 Vesicular Antibody, EV Displayed (VS-0425-YC417)

CAT#: VS-0425-YC417

The Recombinant Anti-KCNK4 Vesicular Antibody, EV Displayed (VS-0425-YC417) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to KCNK4-expressed cells or tissues. The KCNK4 belongs to the potassium channel family, linked to sensory perception of stimuli.

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • KCNK4
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG2a
  • Species Reactivity
  • Mouse
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Potassium two pore domain channel subfamily K member 4
  • Biological Process
  • Ion transport, Potassium transport, Transport
  • Molecular Function
  • Ion channel, Potassium channel, Voltage-gated channel
  • Introduction
  • Predicted to enable identical protein binding activity and monoatomic cation channel activity. Involved in detection of mechanical stimulus involved in sensory perception of touch; sensory perception of pain; and sensory perception of temperature stimulus. Predicted to be located in node of Ranvier. Predicted to be part of potassium channel complex. Predicted to be active in plasma membrane. Is expressed in 2-cell stage embryo; blastocyst; early conceptus; secondary oocyte; and spermatid. Orthologous to human KCNK4 (potassium two pore domain channel subfamily K member 4).
  • Alternative Names
  • Catsperz, MLZ-622, TRAAK, TRAAKt, Tex40
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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