Recombinant Anti-KLRC1 Vesicular Antibody, EV Displayed (VS-0425-YC152)
CAT#: VS-0425-YC152
The Recombinant Anti-KLRC1 Vesicular Antibody, EV Displayed (VS-0425-YC152) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to KLRC1-expressed cells or tissues. The KLRC1 is a natural killer cell lectin-like receptor family member involved in recognizing MHC class I HLA-E molecules through interactions with the KLRD1/CD94 complex.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/58052/1522_A10_3_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (HeLa, Karpas-707)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134545-KLRC1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- KLRC1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Killer cell lectin like receptor C1
- Biological Process
- Adaptive immunity, Host-virus interaction, Immunity, Innate immunity
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane
- Introduction
- Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Alternative Names
- CD159a, NKG2, NKG2-A, NKG2-B
- Gene ID
- 3821
- UniProt ID
- P26715
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC152. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "KLRC1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-604 | Recombinant Anti-human KLRC1 Antibody | WB, Neut, FuncS | IgG |
| MHH-604 | Recombinant Human Anti-human KLRC1 Antibody | ELISA, WB, FC, FuncS | IgG |
| MOB-0225CT | Recombinant Mouse anti-Human KLRC1 Monoclonal antibody (NN0598-9T47) | WB | |
| MOR-1968 | Hi-Affi™ Recombinant Rabbit Anti-KLRC1 Monoclonal Antibody (DS1968AB) | IHC-P, WB | IgG |
| VS-0224-XY78 | Mouse Anti-KLRC1 Recombinant Antibody (VS-0224-XY78) | FC, IF, IHC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-604-F(E) | Recombinant Anti-human KLRC1 Antibody Fab Fragment | RIA, ELISA, FuncS | Fab |
| MHH-604-F(E) | Recombinant Human Anti-human KLRC1 Antibody Fab Fragment | Neut, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-604-S(P) | Recombinant Anti-human KLRC1 Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| MHH-604-S(P) | Recombinant Human Anti-human KLRC1 Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0338CL | Human Anti-KLRC1 Recombinant Antibody (TAB-0338CL) | IHC | Humanized antibody |
| TAB-0338CL-S(P) | Human Anti-KLRC1 Recombinant Antibody; scFv Fragment (TAB-0338CL-S(P)) | ELISA | Humanized scFv |
| TAB-0338CL-F(E) | Human Anti-KLRC1 Recombinant Antibody; Fab Fragment (TAB-0338CL-F(E)) | ELISA | Humanized Fab |
| TAB-437CQ | Anti-Human KLRC1 Recombinant Antibody (TAB-437CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG4, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-437CQ | Afuco™ Anti-KLRC1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-437CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY157 | Human Anti-KLRC1 scFv-Fc Chimera (VS-0425-FY157) | ELISA, IHC, FC, IP, IF | Human IgG4, scFv-Fc |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, IP, IF, FuncS, FC, Neut, ELISA
Application: IHC, ELISA, FC, WB, ADCC, FuncS
Application: ELISA, FC, IF, WB
Application: Block, IP, IF, FC
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: Neut, ELISA, WB, SPR, IF, EM
Application: ELISA, Neut, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
