Recombinant Mouse Anti-KRT1 Antibody (VS4-CJ1) (CAT#: VS4-CJ1)
This mouse anti-KRT1 antibody is a product that recognizes human KRT1. The immunogen of this antibody is a synthesized peptide derived from human Cytokeratin 1. The mAb has been tested for use in ELISA, Immunohistochemistry (1:20-1:200).
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Normal Tissue
RNA Expression
Figure 1 High expression in skin 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17917/42356_B_7_1_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17917/42356_B_7_1_val_selected.jpg
Figure 2 Low expression in kidney
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17917/42356_A_9_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17917/42356_A_9_5_val_selected.jpg
Figure 3 IHC staining of human skin
(Immunohistochemical staining of human skin shows strong cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62908/ihc_selected.jpg
(Immunohistochemical staining of human skin shows strong cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62908/ihc_selected.jpg
Figure 4 Skin
(Cells in corneal layer Staining: Medium Intensity: Moderate Quantity: 75%-25% Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Cells in spinous layer Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17917/42356_B_6_8.jpg
(Cells in corneal layer Staining: Medium Intensity: Moderate Quantity: 75%-25% Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Cells in spinous layer Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17917/42356_B_6_8.jpg
Figure 5 RNA cell line category: Group enriched (HaCaT, hTCEpi)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167768-KRT1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167768-KRT1
Specifications
- Immunogen
- Synthesized peptide derived from human Cytokeratin 1
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human KRT1
- Species Reactivity
- Human
- Applications
- ELISA, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Immunogen affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.5% BSA, PBS
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Immunohistochemistry (1:20-1:200).
Target
- Alternative Names
- KRTA; K1; CK1; EHK; EHK1; EPPK; KRT1A; NEPPK; Keratin type II cytoskeletal 1; 67 kDa cytokeratin; Cytokeratin-1; Hair alpha protein; Keratin-1; Type-II keratin Kb1
- Gene ID
- 3848
- UniProt ID
- P04264
- Long Name
- Keratin 1
- Sequence Similarities
- Belongs to the intermediate filament family.
- Cellular Localization
- Cell membrane, Intermediate filament, Keratin, Membrane
- Post Translation Modifications
- Undergoes deimination of some arginine residues (citrullination).
- Protein Refseq
- NP_006112.3
- Function
- May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.
Recommended Products
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1627z | Mouse Anti-KRT1 Recombinant Antibody (clone 27C7) | WB, FC, IF, IHC | Mouse IgG1 |
| MRO-0433-CN | Recombinant Rabbit Anti-KRT1 Monoclonal Antibody (CBACN-173) | WB, IHC | Rabbit IgG |
| ZG-0227J | Mouse Anti-KRT1 Recombinant Antibody (ZG-0227J) | IHC-P, IF | Mouse IgG |
| ZG-0228J | Mouse Anti-KRT1 Recombinant Antibody (ZG-0228J) | IHC-P, IF | Mouse IgG |
| ZG-0229J | Mouse Anti-KRT1 Recombinant Antibody (ZG-0229J) | IHC-P, IF, WB | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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