Recombinant Mouse Anti-KRT10 Antibody (clone 7A5A6) (CAT#: VS3-FY804)

• Host Species
• Mouse

• Type
• Mouse IgG1

• Clone
• 7A5A6

• Applications
• Enzyme-linked Immunosorbent Assay, Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry

• Conjugate
• Unconjugated

• Purity
• >95% as determined by SDS-PAGE

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry.

• Alternative Names
• Keratin 10; Keratin 10, Type I; Cytokeratin 10; CK-10; KPP; K10; Keratosis Palmaris Et Plantaris; Keratin, Type I Cytoskeletal 10

• Gene ID
• 3858

• UniProt ID
• P13645

• Sequence Similarities
• Belongs to the intermediate filament family.

• Cellular Localization
• Intermediate filament, Keratin, Secreted

• Protein Refseq
• NP_000412.3

• Function
• Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity).
  Involved in the maintenance of cell layer development and keratin filament bundles in suprabasal cells of the epithelium (By similarity).
  (Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nasal colonization.
  (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Reduction of levels of KRT10 keratin decrease adherence, overexpression increases adherence. Neither protein has to be glycosylated for the interaction to occur.

Secondary Antibody

• 2ND-047CQ
• Goat Anti-Mouse IgG1 Antibody, R-PE

• 2RD-A1460-YJ
• Goat Anti-Mouse IgG1 Secondary antibody

Isotype Control

• MOB-065CQ
• Mouse IgG1 Isotype Control Antibody

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