Recombinant Anti-LAMP5 Vesicular Antibody, EV Displayed (VS-0425-YC317)

CAT#: VS-0425-YC317

The Recombinant Anti-LAMP5 Vesicular Antibody, EV Displayed (VS-0425-YC317) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LAMP5-expressed cells or tissues. The LAMP5 is involved in protein localization to organelles and is found in membranes like endoplasmic reticulum-Golgi structures.

Gene Expression
Figure 1 IF staining of human cell line SH-SY5Y Figure 2 IF staining of human cell line REH Figure 3 RNA cell line category: Cell line enhanced (Karpas-707, SH-SY5Y, THP-1)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • LAMP5
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG2b kappa
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Lysosomal associated membrane protein family member 5
  • Cellular Localization
  • Cytosol, Mitotic spindle, Centriolar satellite
  • Introduction
  • Predicted to be involved in establishment of protein localization to organelle. Located in endoplasmic reticulum-Golgi intermediate compartment membrane; endosome membrane; and plasma membrane.
  • Alternative Names
  • BAD-LAMP, C20orf103, dJ1119D9.3, UNC-46
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