Recombinant Anti-LILRB4 Vesicular Antibody, EV Displayed (VS-0425-YC95)
CAT#: VS-0425-YC95
The Recombinant Anti-LILRB4 Vesicular Antibody, EV Displayed (VS-0425-YC95) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LILRB4-expressed cells or tissues. The LILRB4 is a receptor similar to LILRB3, involved in immune response regulation, also functioning in antigen capture and presentation.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (Karpas-707)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186818-LILRB4
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Recombinant Antibody
- Application
- Block, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LILRB4
- Host Animal
- Human
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Leukocyte immunoglobulin like receptor B4
- Biological Process
- Adaptive immunity, Immunity
- Molecular Function
- Receptor
- Introduction
- This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
- Alternative Names
- CD85k, HM18, ILT3, LIR-5, LIR5
- Gene ID
- 11006
- UniProt ID
- Q8NHJ6
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1298-VHH | Recombinant Anti-Human LILRB4 VHH Single Domain Antibody | FUNC, FA, IP, ChiP | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-705LC | Mouse Anti-LILRB4 Recombinant Antibody (TAB-705LC) | ELISA, FC | Mouse IgG1 |
| TAB-705LC-S(P) | Mouse Anti-LILRB4 Recombinant Antibody; scFv Fragment (TAB-705LC-S(P)) | ELISA, FC | Mouse scFv |
| TAB-705LC-F(E) | Mouse Anti-LILRB4 Recombinant Antibody; Fab Fragment (TAB-705LC-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-706LC | Human Anti-LILRB4 Recombinant Antibody (TAB-706LC) | Block, ELISA, FC, Inhib | Chimeric antibody (mouse/human) |
| TAB-706LC-S(P) | Mouse Anti-LILRB4 Recombinant Antibody; scFv Fragment (TAB-706LC-S(P)) | ELISA, FC | Mouse scFv |
| TAB-706LC-F(E) | Human Anti-LILRB4 Recombinant Antibody; Fab Fragment (TAB-706LC-F(E)) | ELISA, FC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-707LC | Human Anti-LILRB4 Recombinant Antibody (TAB-707LC) | FuncS | Humanized antibody |
| TAB-707LC-S(P) | Human Anti-LILRB4 Recombinant Antibody; scFv Fragment (TAB-707LC-S(P)) | ELISA, FC | Humanized scFv |
| TAB-707LC-F(E) | Human Anti-LILRB4 Recombinant Antibody; Fab Fragment (TAB-707LC-F(E)) | ELISA, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0363-YC | Mouse Anti-LILRB4 Recombinant Antibody (HPAB-N0363-YC) | FC, ELISA, FuncS | Mouse IgG |
| FN-257CQ | Recombinant Mouse Anti-LILRB4 Antibody (ZM4.1) | FC, FuncS, Neut, IP | Mouse IgG1 |
| PABJ-0128 | Human Anti-LILRB4 Recombinant Antibody (PABJ-0128) | ELISA, Block, ADCC | Human IgG |
| VS3-WK1318 | Rabbit Anti-LILRB4 Recombinant Antibody (VS3-WK1318) | ELISA, IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0363-YC-S(P) | Mouse Anti-LILRB4 Recombinant Antibody; scFv Fragment (HPAB-N0363-YC-S(P)) | FC, ELISA, FuncS | Mouse scFv |
| PABJ-0128-S(P) | Human Anti-LILRB4 Recombinant Antibody scFv Fragment (PABJ-0128-S(P)) | ELISA, Block, ADCC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0363-YC-F(E) | Mouse Anti-LILRB4 Recombinant Antibody; Fab Fragment (HPAB-N0363-YC-F(E)) | FC, ELISA, FuncS | Mouse Fab |
| PABJ-0128-F(E) | Human Anti-LILRB4 Recombinant Antibody Fab Fragment (PABJ-0128-F(E)) | ELISA, Block, ADCC | Human Fab |
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