Recombinant Anti-Ly6E Vesicular Antibody, EV Displayed (VS-0425-YC557)

CAT#: VS-0425-YC557

The Recombinant Anti-Ly6E Vesicular Antibody, EV Displayed (VS-0425-YC557) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to Ly6E-expressed cells or tissues. Ly6E influences viral entry and receptor activity, involved in pathways like acetylcholine signaling. It is expressed in various tissues, including the brain and immune system.

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, MCF7)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • Ly6E
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG1 kappa
  • Species Reactivity
  • Mouse, Pan troglodytes
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Lymphocyte antigen 6 family member E
  • Biological Process
  • Host-virus interaction
  • Introduction
  • Enables acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Involved in negative regulation of viral entry into host cell. Acts upstream of or within several processes, including acetylcholine receptor signaling pathway; epinephrine secretion; and ventricular cardiac muscle tissue morphogenesis. Predicted to be located in side of membrane and synapse. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and immune system. Orthologous to human LY6E (lymphocyte antigen 6 family member E).
  • Alternative Names
  • Ly67; Tsa1; RIG-E; Sca-2; TSA-1
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VS-0525-XY4134 Anti-LY6E Immunohistochemistry Kit IHC
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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