Recombinant Anti-MANSC1 Vesicular Antibody, EV Displayed (VS-0425-YC587)
CAT#: VS-0425-YC587
The Recombinant Anti-MANSC1 Vesicular Antibody, EV Displayed (VS-0425-YC587) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to MANSC1-expressed cells or tissues. MANSC1 (MANSC Domain Containing 1) is a protein associated with Temtamy Syndrome and Autosomal Dominant Intellectual Developmental Disorder 6.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7955/44_A11_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/44_B11_1_selected.jpg
Normal Tissue
Figure 3 IHC staining of human oral mucosa
Immunohistochemical staining of human oral mucosa shows strong cytoplasmic positivity in basal layer of squamous epithelium.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7955/22341_A_9_1_selected.jpg
Normal Tissue
Figure 4 IHC staining of human cerebellum
Immunohistochemical staining of human cerebellum shows weak cytoplasmic positivity in Purkinje cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_B_8_8_selected.jpg
Normal Tissue
Figure 5 Salivary gland
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_B_1_1.jpg
Normal Tissue
Figure 6 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_A_7_3.jpg
Normal Tissue
Figure 7 Liver
Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_A_8_4.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (HUVEC TERT2, OE19, RPTEC TERT1)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111261-MANSC1
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- MANSC1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "MANSC1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0283-FY | Mouse Anti-MANSC1 Recombinant Antibody (clone ACT35-51_1B4A7D) | IP, F | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0283-FY-S(P) | Mouse Anti-MANSC1 Recombinant Antibody (clone ACT35-51_1B4A7D); scFv Fragment | IP, F | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0283-FY-F(E) | Mouse Anti-MANSC1 Recombinant Antibody (clone ACT35-51_1B4A7D); Fab Fragment | IP, F | Mouse Fab, κ |
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