Recombinant Anti-MANSC1 Vesicular Antibody, EV Displayed (VS-0425-YC587) (CAT#: VS-0425-YC587)
The Recombinant Anti-MANSC1 Vesicular Antibody, EV Displayed (VS-0425-YC587) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to MANSC1-expressed cells or tissues. MANSC1 (MANSC Domain Containing 1) is a protein associated with Temtamy Syndrome and Autosomal Dominant Intellectual Developmental Disorder 6.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7955/44_A11_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7955/44_A11_2_selected.jpg

Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/44_B11_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/44_B11_1_selected.jpg

Figure 3 IHC staining of human oral mucosa
(Immunohistochemical staining of human oral mucosa shows strong cytoplasmic positivity in basal layer of squamous epithelium.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7955/22341_A_9_1_selected.jpg
(Immunohistochemical staining of human oral mucosa shows strong cytoplasmic positivity in basal layer of squamous epithelium.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7955/22341_A_9_1_selected.jpg

Figure 4 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows weak cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_B_8_8_selected.jpg
(Immunohistochemical staining of human cerebellum shows weak cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_B_8_8_selected.jpg

Figure 5 Salivary gland
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_B_1_1.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_B_1_1.jpg

Figure 6 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_A_7_3.jpg

Figure 7 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_A_8_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7956/22402_A_8_4.jpg

Figure 8 RNA cell line category: Cell line enhanced (HUVEC TERT2, OE19, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111261-MANSC1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111261-MANSC1
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- MANSC1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- MANSC domain containing 1
- Cellular Localization
- Vesicles, Golgi apparatus
- Introduction
- MANSC1 (MANSC Domain Containing 1) is a Protein Coding gene.
- Alternative Names
- FLJ10298, LOH12CR3
- Gene ID
- 54682
- UniProt ID
- Q9H8J5
Downloads
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IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0283-FY | Mouse Anti-MANSC1 Recombinant Antibody (clone ACT35-51_1B4A7D) | IP, F | Mouse IgG2a, κ |
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