Recombinant Anti-MICB Vesicular Antibody, EV Displayed (VS-0425-YC458)
CAT#: VS-0425-YC458
The Recombinant Anti-MICB Vesicular Antibody, EV Displayed (VS-0425-YC458) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to MICB-expressed cells or tissues. The MICB is an antigen recognized by NK cells, involved in cytolytic responses and stress-induced expression.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line BJ
Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm, plasma membrane & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64618/1446_E9_5_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204516-MICB
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- MICB
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- MHC class I polypeptide-related sequence B
- Biological Process
- Adaptive immunity, Cytolysis, Host-virus interaction, Immunity
- Cellular Localization
- Golgi apparatus, Plasma membrane, Nucleoplasm
- Introduction
- This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
- Alternative Names
- PERB11.2
- Gene ID
- 4277
- UniProt ID
- Q29980
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "MICB"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3208z | Mouse Anti-MICB Recombinant Antibody (clone 25D2) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| MOB-1235CT | Recombinant Mouse anti-Human MICB Monoclonal antibody (NN0584-4D48) | FC, WB | |
| HPAB-N0178-YC | Mouse Anti-MICB Recombinant Antibody (HPAB-N0178-YC) | ELISA, FC | Mouse IgG2 |
| VS-0723-WK236 | Rabbit Anti-MICB Recombinant Antibody (VS-0723-WK236) | ELISA, FC | Rabbit IgG |
| VS7-0425-WR384 | Mouse Anti-MICB Recombinant Antibody (clone 1B2F11) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1740CQ | Recombinant Mouse Anti-MICB Antibody (CBL145) | FC, WB, IHC, Neut | IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4328 | Hi-Affi™ Recombinant Rabbit Anti-MICB Monoclonal Antibody (SI417DS) | WB | IgG |
| MOR-4329 | Hi-Affi™ Recombinant Rabbit Anti-MICB Monoclonal Antibody (SI418DS) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0178-YC-S(P) | Mouse Anti-MICB Recombinant Antibody; scFv Fragment (HPAB-N0178-YC-S(P)) | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0178-YC-F(E) | Mouse Anti-MICB Recombinant Antibody; Fab Fragment (HPAB-N0178-YC-F(E)) | ELISA, FC | Mouse Fab |
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