Recombinant Rabbit Anti-MMP1 Capture Antibody (clone R87-8B-9)
CAT#: VS3-WK1848
This antibody is a rabbit recombinant antibody against human MMP1. It was developed by immunization of rabbit with recombinant human MMP1 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. The sandwich ELISA was established using matched antibody pair R87-8B-9 and R71-4W-3. The clone R87-8B-9 can be used as a capture antibody in ELISA analysis to identify human MMP1.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4920/1_B2_2_selected.jpg
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Specifications
- Immunogen
- Recombinant human MMP1 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human MMP1
- Species Reactivity
- Human
- Clone
- R87-8B-9
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Matrix Metallopeptidase 1; Interstitial Collagenase; Fibroblast Collagenase; EC 3.4.24.7; CLG; Matrix Metalloproteinase 1 (Interstitial Collagenase); Matrix Metallopeptidase 1 (Interstitial Collagenase)
- Gene ID
- 4312
- UniProt ID
- P03956
- Long Name
- Matrix Metallopeptidase 1
- Sequence Similarities
- Belongs to the peptidase M10A family.
- Cellular Localization
- Extracellular matrix, Secreted
- Post Translation Modifications
- Undergoes autolytic cleavage to two major forms (22 kDa and 27 kDa). A minor form (25 kDa) is the glycosylated form of the 22 kDa form. The 27 kDa form has no activity while the 22/25 kDa form can act as activator for collagenase.
Tyrosine phosphorylated in platelets by PKDCC/VLK.
- Protein Refseq
- NP_002412.1
- Function
- Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X.
In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
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Related Diseases
Rheumatoid Arthritis
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Detection antibody
Isotype Control
- CAT
- Product Name
Secondary Antibody
See other products for "MMP1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1937MZ | Recombinant Mouse Anti-Human MMP1 Antibody (clone 4B0.4) | WB | Mouse antibody |
| MRO-2036-CN | Rabbit Anti-MMP1 Polyclonal Antibody (MRO-2036-CN) | WB, IF, IHC | Rabbit IgG |
| ZG-0716F | Mouse Anti-MMP1 Recombinant Antibody (clone 3B6) | WB, IHC | Mouse IgG1 |
| VS3-QX777 | Mouse Anti-MMP1 Recombinant Antibody (clone 6A5) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS7-0425-WR398 | Mouse Anti-MMP1 Monoclonal Antibody (VS7-0425-WR398) | WB, IHC-P, IF, ICC, FC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1742CQ | Recombinant Mouse Anti-MMP1 Antibody (CBL461) | WB, IHC, IP, Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2247 | Hi-Affi™ Recombinant Rabbit Anti-MMP1 Monoclonal Antibody (DS2247AB) | FC, ICC, IHC-Fr, IHC-P, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1353 | Anti-MMP1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4436 | Anti-Mouse MMP1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4435 | Anti-Human MMP1 Immunohistochemistry Kit | IHC |
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