Recombinant Anti-MPIG6B Vesicular Antibody, EV Displayed (VS-0425-YC415) (CAT#: VS-0425-YC415)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• MPIG6B

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Megakaryocyte and platelet inhibitory receptor G6b

• Molecular Function
• Heparin-binding, Receptor

• Cellular Localization
• Golgi apparatus, Nucleoplasm, Endoplasmic reticulum, Plasma membrane, Cytosol

• Introduction
• This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.

• Alternative Names
• C6orf25, G6b, G6b-B, NG31

• Gene ID
• 80739

• UniProt ID
• O95866

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