Recombinant Anti-MTDH Vesicular Antibody, EV Displayed (VS-0425-YC556)
CAT#: VS-0425-YC556
The Recombinant Anti-MTDH Vesicular Antibody, EV Displayed (VS-0425-YC556) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to MTDH-expressed cells or tissues. MTDH is involved in pathways such as C-MYC activation and linked to diseases like gallbladder adenocarcinoma. MTDH assists in double-stranded RNA binding.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68204/1894_H7_3_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human small intestine
Immunohistochemical staining of human small intestine shows cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_4_2_selected.jpg
Subcellular Location and Protein Expression
Figure 4 IHC staining of human cerebral corte
Immunohistochemical staining of human cerebral cortex shows strong positivity.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68204/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 5 IHC staining of human smooth muscle
Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68205/ihc_selected.jpg
Normal Tissue
Figure 6 Colon
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_7_3.jpg
Normal Tissue
Figure 7 Liver
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_7_4.jpg
Normal Tissue
Figure 8 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_7_5.jpg
Normal Tissue
Figure 9 Testis
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_6_6.jpg
Normal Tissue
Figure 10 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_8_8.jpg
RNA Expression
Figure 11 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000147649-MTDH
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- MTDH
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Metadherin
- Cellular Localization
- Endoplasmic reticulum
- Introduction
- MTDH (Metadherin) is a Protein Coding gene. Diseases associated with MTDH include Gallbladder Adenocarcinoma and Nervous System Disease. Among its related pathways are Validated targets of C-MYC transcriptional activation and Gastric Cancer Network 2. Gene Ontology (GO) annotations related to this gene include double-stranded RNA binding.
- Alternative Names
- 3D3, AEG-1, LYRIC
- Gene ID
- 92140
- UniProt ID
- Q86UE4
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC556. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MTDH"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-678 | Recombinant Anti-human MTDH Antibody | ELISA, WB, IF, FuncS | IgG |
| HPAB-0497-CN | Mouse Anti-MTDH Recombinant Antibody (clone 1E3) | WB, ELISA, IHC | Mouse IgG1, κ |
| VS3-FY969 | Recombinant Mouse Anti-MTDH Antibody (clone 1F3A3) | ELISA, WB, IHC, ICC, FC | Mouse IgG1 |
| VS7-0425-WR380 | Mouse Anti-MTDH Monoclonal Antibody (clone 2F11C3) | WB, IHC, FC | Mouse IgG1 |
| VS7-0425-WR432 | Mouse Anti-MTDH Monoclonal Antibody (VS7-0425-WR432) | WB, IHC-P, IF, FC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-678-F(E) | Recombinant Anti-human MTDH Antibody Fab Fragment | IP, FuncS | Fab |
| MHH-678-F(E) | Recombinant Human Anti-human MTDH Antibody Fab Fragment | WB, IF, FuncS | Fab |
| HPAB-0497-CN-F(E) | Mouse Anti-MTDH Recombinant Antibody (clone 1E3); Fab Fragment | WB, ELISA, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-678-S(P) | Recombinant Anti-human MTDH Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| MHH-678-S(P) | Recombinant Human Anti-human MTDH Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| HPAB-0497-CN-S(P) | Mouse Anti-MTDH Recombinant Antibody (clone 1E3); scFv Fragment | WB, ELISA, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2316 | Hi-Affi™ Recombinant Rabbit Anti-MTDH Monoclonal Antibody (DS2316AB) | WB, IHC, ICC | IgG |
| MOR-4646 | Hi-Affi™ Recombinant Rabbit Anti-MTDH Monoclonal Antibody (TH159DS) | WB, IF, ICC, IHC-P, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1386 | Anti-MTDH Immunohistochemistry Kit | IHC | |
| VS-0525-XY4559 | Anti-Mouse MTDH Immunohistochemistry Kit | IHC | |
| VS-0525-XY4558 | Anti-Human MTDH Immunohistochemistry Kit | IHC | |
| VS-0525-XY4560 | Anti-Rat MTDH Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: IHC, ELISA, FC, WB, ADCC, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, FC, Inhib, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
