Recombinant Anti-MUC17 Vesicular Antibody, EV Displayed (VS-0425-YC158)
CAT#: VS-0425-YC158
The Recombinant Anti-MUC17 Vesicular Antibody, EV Displayed (VS-0425-YC158) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to MUC17-expressed cells or tissues. The MUC17 is a membrane-bound mucin that provides protection to gut epithelial cells, with two transcript variants identified for this gene.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human small intestine
High expression. RNA expression: 42.7 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31634/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human liver
Low expression. RNA expression: 0.0 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31634/72331_A_9_4_val_selected.jpg
Normal Tissue
Figure 3 Colon
Enterocytes
Staining: Not detected
Intensity: Weak
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31634/72331_A_9_3.jpg
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- MUC17
- Host Animal
- Human
- Antibody Isotype
- IgG1 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Mucin 17, cell surface associated
- Introduction
- The protein encoded by this gene is a membrane-bound mucin that provides protection to gut epithelial cells. The encoded protein contains about 60 tandem repeats, with each repeat being around 60 aa. N-glycosylation enables the encoded protein to localize on the cell surface, while the C-terminus interacts with the scaffold protein PDZ domain containing 1 (PDZK1). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]
- Gene ID
- 140453
- UniProt ID
- Q685J3
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Datasheet
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COA
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See other products for "MUC17"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-681 | Recombinant Anti-human MUC17 Antibody | ELISA, WB, IP, FuncS | IgG |
| MHH-681 | Recombinant Human Anti-human MUC17 Antibody | WB, IF, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-681-F(E) | Recombinant Anti-human MUC17 Antibody Fab Fragment | WB, IF, FuncS | Fab |
| MHH-681-F(E) | Recombinant Human Anti-human MUC17 Antibody Fab Fragment | WB, FC, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-681-S(P) | Recombinant Anti-human MUC17 Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| MHH-681-S(P) | Recombinant Human Anti-human MUC17 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-407MZ | Mouse Anti-MUC17 Recombinant Antibody (TAB-407MZ) | Cyt, ELISA, FC, FuncS | Mouse IgG1, κ |
| TAB-408MZ | Mouse Anti-MUC17 Recombinant Antibody (TAB-408MZ) | Cyt, ELISA, FC | Mouse IgG1, κ |
| TAB-407MZ-S(P) | Mouse Anti-MUC17 Recombinant Antibody; scFv Fragment (TAB-407MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-408MZ-S(P) | Mouse Anti-MUC17 Recombinant Antibody; scFv Fragment (TAB-408MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-407MZ-F(E) | Mouse Anti-MUC17 Recombinant Antibody; Fab Fragment (TAB-407MZ-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-409MZ | Human Anti-MUC17 Recombinant Antibody (TAB-409MZ) | ELISA, FuncS, FC, ADCC | Chimeric antibody (mouse/human) |
| TAB-410MZ | Human Anti-MUC17 Recombinant Antibody (TAB-410MZ) | ELISA, FC, ADCC | Chimeric antibody (mouse/human) |
| TAB-409MZ-S(P) | Mouse Anti-MUC17 Recombinant Antibody; scFv Fragment (TAB-409MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-410MZ-S(P) | Mouse Anti-MUC17 Recombinant Antibody; scFv Fragment (TAB-410MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-409MZ-F(E) | Human Anti-MUC17 Recombinant Antibody; Fab Fragment (TAB-409MZ-F(E)) | ELISA, FC | Chimeric antibody (mouse/human) |
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