Recombinant Anti-NCAM1 Vesicular Antibody, EV Displayed (VS-0425-YC218) (CAT#: VS-0425-YC218)
The Recombinant Anti-NCAM1 Vesicular Antibody, EV Displayed (VS-0425-YC218) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to NCAM1-expressed cells or tissues. The NCAM1 is a cell adhesion protein, part of the immunoglobulin superfamily, mediating cell interactions during development. It influences T and dendritic cell expansion.

(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/if_selected.jpg

(Neuropil
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/100448_B_9_5.jpg

(Peripheral nerve/ganglion
Staining:
High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/100448_A_8_3.jpg

(Peripheral nerve
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/100448_B_1_7.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000149294-NCAM1

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000149294-NCAM1
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- NCAM1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Neural cell adhesion molecule 1
- Biological Process
- Cell adhesion, Host-virus interaction
- Molecular Function
- Host cell receptor for virus entry, Receptor
- Cellular Localization
- Plasma membrane, Cytosol
- Introduction
- This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
- Alternative Names
- CD56, NCAM
- Gene ID
- 4684
- UniProt ID
- P13591
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "NCAM1"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-188 | Humanized Anti-NCAM1 Recombinant Antibody (clone Lorvotuzumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | Humanized (from mouse) IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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