Recombinant Anti-PDPN Vesicular Antibody, EV Displayed (VS-0425-YC272)
CAT#: VS-0425-YC272
The Recombinant Anti-PDPN Vesicular Antibody, EV Displayed (VS-0425-YC272) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to PDPN-expressed cells or tissues. The PDPN is a glycoprotein distributed across tissues, with potential as a lung injury marker.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line EFO-21
Immunofluorescent staining of human cell line EFO-21 shows localization to plasma membrane & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7949/1907_B7_4_selected.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8376/24701_A_9_3.jpg
Normal Tissue
Figure 3 Testis
Leydig cells Staining: Low Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8376/24701_A_4_6.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (AF22, EFO-21, HAP1, HHSteC, NTERA-2, SuSa, TIME)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162493-PDPN
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- PDPN
- Host Animal
- Rat
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Podoplanin
- Biological Process
- Cell shape
- Molecular Function
- Developmental protein
- Cellular Localization
- Plasma membrane, Cell Junctions, Mitochondria
- Introduction
- This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.
- Alternative Names
- aggrus, D2-40, Gp38, GP40, PA2.26, T1A-2
- Gene ID
- 10630
- UniProt ID
- Q86YL7
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-655 | Mouse Anti-PDPN Recombinant Antibody (PABL-655) | WB, FuncS | Mouse IgG2a |
| MOB-1618CT | Recombinant Mouse anti-Human PDPN Monoclonal antibody (29I6) | FC, ICC, IF, IHC-Fr, IHC-P, WB | |
| FAMAB-1870CQ | Mouse Anti-PDPN Recombinant Antibody (clone PMab-1) | WB, Block, ELISA, IHC | Mouse IgG1 |
| ZG-0507U | Rabbit Anti-PDPN Recombinant Antibody (clone 4E6) | ELISA | Rabbit IgG |
| VS3-FY2118 | Rabbit Anti-PDPN Recombinant Antibody (clone R77-1S-2) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-650 | Mouse Anti-PDPN Recombinant Antibody; Fab Fragment (PFBL-650) | WB, FuncS | Mouse Fab |
| HPAB-0502-CN-F(E) | Mouse Anti-PDPN Recombinant Antibody; Fab Fragment (HPAB-0502-CN-F(E)) | WB, ELISA, FC, IP | Mouse Fab |
| HPAB-0503-CN-F(E) | Human Anti-PDPN Recombinant Antibody; Fab Fragment (HPAB-0503-CN-F(E)) | WB, ELISA, FC, IP | Human Fab |
| HPAB-0504-CN-F(E) | Mouse Anti-PDPN Recombinant Antibody; Fab Fragment (HPAB-0504-CN-F(E)) | WB, ELISA, FC, IP | Mouse Fab |
| HPAB-0505-CN-F(E) | Human Anti-PDPN Recombinant Antibody; Fab Fragment (HPAB-0505-CN-F(E)) | WB, ELISA, FC, IP | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-650 | Mouse Anti-PDPN Recombinant Antibody; scFv Fragment (PSBL-650) | WB, FuncS | Mouse scFv |
| HPAB-0502-CN-S(P) | Mouse Anti-PDPN Recombinant Antibody; scFv Fragment (HPAB-0502-CN-S(P)) | WB, ELISA, FC, IP | Mouse scFv |
| HPAB-0503-CN-S(P) | Mouse Anti-PDPN Recombinant Antibody; scFv Fragment (HPAB-0503-CN-S(P)) | WB, ELISA, FC, IP | Mouse scFv |
| HPAB-0504-CN-S(P) | Mouse Anti-PDPN Recombinant Antibody; scFv Fragment (HPAB-0504-CN-S(P)) | WB, ELISA, FC, IP | Mouse scFv |
| HPAB-0505-CN-S(P) | Mouse Anti-PDPN Recombinant Antibody; scFv Fragment (HPAB-0505-CN-S(P)) | WB, ELISA, FC, IP | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1055CL | Rat Anti-PDPN Recombinant Antibody (TAB-1055CL) | WB, FC | Rat IgG |
| TAB-1055CL-S(P) | Rat Anti-PDPN Recombinant Antibody; scFv Fragment (TAB-1055CL-S(P)) | SDS-PAGE, WB, FC | Rat scFv |
| TAB-0567CL-S(P) | Mouse Anti-PDPN Recombinant Antibody; scFv Fragment (TAB-0567CL-S(P)) | WB, FC | Mouse scFv |
| TAB-0567CL-F(E) | Mouse Anti-PDPN Recombinant Antibody; Fab Fragment (TAB-0567CL-F(E)) | WB, FC | Mouse Fab |
| TAB-0568CL-F(E) | Mouse Anti-PDPN Recombinant Antibody; Fab Fragment (TAB-0568CL-F(E)) | WB, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1851CQ | Recombinant Hamster Anti-Pdpn Antibody (8.1.1) | BL, IF, WB, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2650 | Hi-Affi™ Recombinant Rabbit Anti-PDPN Monoclonal Antibody (DS2650AB) | FC, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| CBP-215YJL | Recombinant Human Podoplanin Protein | Positive Control, Immunogen, SDS-PAGE, WB, ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1293 | AbPlus™ Anti-PDPN Magnetic Beads (VS-0724-YC1293) | IP, Protein Purification | |
| VS-0424-XY210 | AbPlus™ Anti-PDPN Magnetic Beads (VS-0424-XY210) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5296 | Anti-Mouse PDPN Immunohistochemistry Kit | IHC | |
| VS-0525-XY5297 | Anti-Rat PDPN Immunohistochemistry Kit | IHC |
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