Recombinant Anti-PI16 Vesicular Antibody, EV Displayed (VS-0425-YC277) (CAT#: VS-0425-YC277)
The Recombinant Anti-PI16 Vesicular Antibody, EV Displayed (VS-0425-YC277) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to PI16-expressed cells or tissues. The PI16 is predicted to enable peptidase inhibitor activity, impacting cell growth regulation involved in cardiac development.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuropil Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76574/165985_B_8_5.jpg
(Neuropil Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76574/165985_B_8_5.jpg
Figure 2 Colon
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76574/165985_A_8_3.jpg
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76574/165985_A_8_3.jpg
Figure 3 Liver
(Hepatocytes Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76574/165985_A_9_4.jpg
(Hepatocytes Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76574/165985_A_9_4.jpg
Figure 4 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76574/165985_A_9_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76574/165985_A_9_5.jpg
Figure 5 Testis
(Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Peritubular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76574/165985_A_5_6.jpg
(Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Peritubular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76574/165985_A_5_6.jpg
Figure 6 RNA cell line category: Cell line enriched (JURKAT)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164530-PI16
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164530-PI16
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- PI16
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Peptidase inhibitor 16
- Molecular Function
- Protease inhibitor
- Introduction
- Predicted to enable peptidase inhibitor activity. Predicted to act upstream of or within negative regulation of cell growth involved in cardiac muscle cell development. Predicted to be located in extracellular region. Predicted to be active in extracellular space.
- Alternative Names
- CD364, dJ90K10.5, MGC45378, MSMBBP
- Gene ID
- 221476
- UniProt ID
- Q6UXB8
Downloads
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Mouse Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1029CL | Mouse Anti-PI16 Recombinant Antibody (TAB-1029CL) | FC | Mouse IgG |
| TAB-1029CL-S(P) | Mouse Anti-PI16 Recombinant Antibody; scFv Fragment (TAB-1029CL-S(P)) | FC | Mouse scFv |
| TAB-1029CL-F(E) | Mouse Anti-PI16 Recombinant Antibody; Fab Fragment (TAB-1029CL-F(E)) | FC | Mouse Fab |
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