Recombinant Anti-PTK7 Vesicular Antibody, EV Displayed (VS-0425-YC670) (CAT#: VS-0425-YC670)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• PTK7

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Protein tyrosine kinase 7 (inactive)

• Biological Process
• Cell adhesion, Wnt signaling pathway

• Molecular Function
• Receptor

• Cellular Localization
• Plasma membrane, Vesicles, Cytosol

• Introduction
• This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion.

• Alternative Names
• CCK4

• Gene ID
• 5754

• UniProt ID
• Q13308

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