Recombinant Rabbit Anti-PTPN6 Antibody (clone R08-1A0)
CAT#: VS3-FY1226
This product is a recombinant rabbit antibody that recognizes PTPN6. This antibody has been reported for use in Western Blot. The clone R08-1A0 is specific for human, mouse, rat PTPN6. The antigen is synthetic peptide of human shp1.
Specifications
- Immunogen
- Synthetic peptide of human SHP1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat PTPN6
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R08-1A0
- Applications
- Western Blot
- Conjugate
- Unconjugated
- MW
- Calculated MW: 68 kDa; Observed MW: 68 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- PTPN6; HCP; PTP1C; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
- Gene ID
- 5777
- UniProt ID
- P29350
- Sequence Similarities
- Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Phosphorylated on tyrosine residues. Binding of KITLG/SCF to KIT increases tyrosine phosphorylation (By similarity).
Phosphorylation at Tyr-564 enhances phosphatase activity.
- Protein Refseq
- NP_002822.2; NP_536858.1; NP_536859.1
- Function
- Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "PTPN6"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1369CT | Recombinant Mouse anti-Human PTPN6 Monoclonal antibody (2TI02 (22E8D9I6)) | IP, WB | |
| MRO-1389-CN | Recombinant Mouse Anti-PTPN6 Monoclonal Antibody (B5-A4) | WB, IF, IHC | Mouse IgG2b |
| MRO-1390-CN | Recombinant Rabbit Anti-PTPN6 Monoclonal Antibody (CBACN-501) | WB, IF, IHC, IP, FC | Rabbit IgG |
| HPAB-0535-FY | Mouse Anti-PTPN6 Recombinant Antibody (HPAB-0535-FY) | ELISA | Mouse IgG |
| VS3-CJ856 | Rabbit Anti-PTPN6 Recombinant Antibody (VS3-CJ856) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2931 | Hi-Affi™ Recombinant Rabbit Anti-PTPN6 Monoclonal Antibody (DS2931AB) | ICC, IF, WB, IHC-P, FC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1966 | PE-B7/Human PTPN6 (VPSEPGGVL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0535-FY-S(P) | Mouse Anti-PTPN6 Recombinant Antibody; scFv Fragment (HPAB-0535-FY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0535-FY-F(E) | Mouse Anti-PTPN6 Recombinant Antibody; Fab Fragment (HPAB-0535-FY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC284 | AbPlus™ Anti-PTPN6 Magnetic Beads (VS-0724-YC284) | IP, Protein Purification | |
| VS-0724-YC1337 | AbPlus™ Anti-Ptpn6 Magnetic Beads (VS-0724-YC1337) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1824 | Anti-PTPN6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5867 | Anti-Mouse PTPN6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5866 | Anti-Human PTPN6 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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