Recombinant Rabbit Anti-PTPN6 Antibody (clone R08-1A0) (CAT#: VS3-FY1226)
This product is a recombinant rabbit antibody that recognizes PTPN6. This antibody has been reported for use in Western Blot. The clone R08-1A0 is specific for human, mouse, rat PTPN6. The antigen is synthetic peptide of human shp1.
Specific Inquiry
Specifications
- Immunogen
- Synthetic peptide of human SHP1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat PTPN6
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R08-1A0
- Applications
- Western Blot
- Conjugate
- Unconjugated
- MW
- Calculated MW: 68 kDa; Observed MW: 68 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- PTPN6; HCP; PTP1C; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
- Gene ID
- 5777
- UniProt ID
- P29350
- Sequence Similarities
- Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Phosphorylated on tyrosine residues. Binding of KITLG/SCF to KIT increases tyrosine phosphorylation (By similarity).
Phosphorylation at Tyr-564 enhances phosphatase activity.
- Protein Refseq
- NP_002822.2; NP_536858.1; NP_536859.1
- Function
- Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3389z | Mouse Anti-PTPN6 Recombinant Antibody (clone 43C7) | WB, IP, ELISA, ICC | Mouse IgG1 |
| MOB-1369CT | Recombinant Mouse anti-Human PTPN6 Monoclonal antibody (2TI02 (22E8D9I6)) | IP, WB | |
| HPAB-0535-FY | Mouse Anti-PTPN6 Recombinant Antibody (HPAB-0535-FY) | ELISA | Mouse IgG |
| VS3-QX941 | Mouse Anti-PTPN6 Recombinant Antibody (clone 2B7-H7-F8) | WB, IP | Mouse IgG2a |
| VS3-CJ856 | Rabbit Anti-PTPN6 Recombinant Antibody (VS3-CJ856) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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