Recombinant Anti-ROBO4 Vesicular Antibody, EV Displayed (VS-0425-YC496)
CAT#: VS-0425-YC496
The Recombinant Anti-ROBO4 Vesicular Antibody, EV Displayed (VS-0425-YC496) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ROBO4-expressed cells or tissues. ROBO4 facilitates cell-cell adhesion and endothelial barrier formation. ROBO4 is associated with aortic valve disease and pre-eclampsia.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65212/1589_F7_2_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000154133-ROBO4
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ROBO4
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Roundabout guidance receptor 4
- Biological Process
- Angiogenesis, Differentiation
- Molecular Function
- Developmental protein, Receptor
- Cellular Localization
- Plasma membrane
- Introduction
- Predicted to enable cell-cell adhesion mediator activity. Involved in establishment of endothelial barrier. Located in extracellular exosome. Implicated in aortic valve disease 3. Biomarker of pre-eclampsia and thyroid gland carcinoma.
- Alternative Names
- ECSM4, FLJ20798, MRB
- Gene ID
- 54538
- UniProt ID
- Q8WZ75
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC496. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ROBO4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-329CT | Mouse Anti-Robo4 Recombinant Antibody (TAB-329CT) | WB, ELISA, FC, IHC | Mouse IgG2a |
| TAB-329CT-S(P) | Mouse Anti-Robo4 Recombinant Antibody; scFv Fragment (TAB-329CT-S(P)) | WB, ELISA, FC, IHC | Mouse scFv |
| TAB-329CT-F(E) | Mouse Anti-Robo4 Recombinant Antibody; Fab Fragment (TAB-329CT-F(E)) | WB, ELISA, FC, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-330CT | Anti-Human Robo4 Recombinant Antibody (YW79.11) | WB, ELISA, FC | Human antibody |
| TAB-330CT-S(P) | Anti-Human Robo4 Recombinant Antibody scFv Fragment (YW79.11) | WB, ELISA, FC | Human antibody |
| TAB-330CT-F(E) | Anti-Human Robo4 Recombinant Antibody Fab Fragment (YW79.11) | WB, ELISA, FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4396 | Hi-Affi™ Recombinant Rabbit Anti-ROBO4 Monoclonal Antibody (SI487DS) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-076CN | Human Anti-ROBO4 Recombinant Antibody (clone YW71.22) | FC, ELISA, FuncS | Human IgG |
| NS-076CN-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone YW71.22); Fab Fragment | FC, ELISA | Human Fab |
| NS-076CN-S(P) | Human Anti-ROBO4 Recombinant Antibody (clone YW71.22); scFv Fragment | FC, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0045-WJ | Human Anti-ROBO4 Recombinant Antibody (HPAB-0045-WJ) | ELISA, RIA | Humanized IgG2, κ |
| HPAB-N0234-YC | Human Anti-ROBO4 Recombinant Antibody (HPAB-N0234-YC) | FC, Activ | Humanized (mouse/human) IgG |
| HPAB-AP412-YC | Human Anti-ROBO4 Recombinant Antibody (clone cMAb1-1) | ELISA, FC | Chimeric (mouse/human) IgG1 |
| HPAB-AP413-YC | Human Anti-ROBO4 Recombinant Antibody (clone cMAb1-2) | ELISA, FC | Chimeric (mouse/human) IgG2 |
| HPAB-J0217-YC | Human Anti-ROBO4 Recombinant Antibody (clone YW71.6) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0045-WJ-S(P) | Human Anti-ROBO4 Recombinant Antibody; scFv Fragment (HPAB-0045-WJ-S(P)) | ELISA, RIA | Humanized scFv |
| HPAB-N0234-YC-S(P) | Human Anti-ROBO4 Recombinant Antibody; scFv Fragment (HPAB-N0234-YC-S(P)) | FC, Activ | Humanized scFv |
| HPAB-AP412-YC-S(P) | Human Anti-ROBO4 Recombinant Antibody (clone cMAb1-1); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-AP413-YC-S(P) | Human Anti-ROBO4 Recombinant Antibody (clone cMAb1-2); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-1902-FY-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone MR7); scFv Fragment | ELISA, Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0217-YC-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone YW71.6); Fab Fragment | ELISA | Human Fab |
| HPAB-J0218-YC-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone YW71.1); Fab Fragment | ELISA | Human Fab |
| HPAB-J0219-YC-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone YW79.1); Fab Fragment | ELISA | Human Fab |
| HPAB-J0220-YC-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone YW79.8); Fab Fragment | ELISA | Human Fab |
| HPAB-J0221-YC-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone YW71.22.S1.16); Fab Fragment | ELISA, FC | Human Fab |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, WB
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
