Recombinant Mouse Anti-S100A6 Antibody (clone 4B1-8B10-8D8)
CAT#: VS3-FY1297
This product is a recombinant mouse antibody that recognizes S100A6. This antibody has been reported for use in Immunohistochemistry-Paraffin. The clone 4B1-8B10-8D8 is specific for human S100A6. The antigen is synthetic peptide derived from human s100a6.
Gene Expression
Tested Data
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7575/18_B10_1_selected.jpg
Normal Tissue
Figure 2 Urinary bladder
High expression in urinary bladder
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7575/21633_A_4_5_val_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40549/84815_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2601/6726_A_9_4.jpg
Normal Tissue
Figure 5 Pancreas
Exocrine glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2601/6726_A_3_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2601/6726_A_8_5.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2601/6726_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (OE19, RPTEC TERT1)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000197956-S100A6
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IHC-P
Figure 1. Recombinant Mouse Anti-S100A6 Antibody (clone 4B1-8B10-8D8) in IHC-P.
Immunohistochemical analysis of paraffin-embedded human prostate using S100 alpha 6 antibody. High pressure and high temperature sodium citrate pH 6.0 for antigen retrieval.
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Specifications
- Immunogen
- Synthetic peptide derived from human S100A6.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human S100A6
- Species Reactivity
- Human
- Clone
- 4B1-8B10-8D8
- Applications
- Immunohistochemistry-Paraffin
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity Chromatography
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS, pH 7.3, 50% glycerol, 0.5% BSA
- Preservative
- 0.02% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry-Paraffin: 1/100-1/500
Target
- Alternative Names
- S100 Calcium Binding Protein A6; Prolactin Receptor-Associated Protein; Growth Factor-Inducible Protein 2A9; Calcyclin; MLN 4; CACY; PRA; S100 Calcium-Binding Protein A6 (Calcyclin)
- Gene ID
- 6277
- UniProt ID
- P06703
- Sequence Similarities
- Belongs to the S-100 family.
- Cellular Localization
- Cell membrane, Cytoplasm, Membrane, Nucleus
- Post Translation Modifications
- The N-terminus is blocked.
- Protein Refseq
- NP_055439.1
- Function
- May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
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Reconstitution Buffer
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See other products for "S100A6"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0523MZ | Chicken Anti-S100A6 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3156 | Hi-Affi™ Recombinant Rabbit Anti-S100A6 Monoclonal Antibody (DS3156AB) | ELISA, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX995 | Mouse Anti-S100A6 Recombinant Antibody (clone 3E11-E9-D8) | WB | Mouse IgG1 |
| VS3-WK407 | Rabbit Anti-S100A6 Recombinant Antibody (clone JF0976) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
| VS3-CJ441 | Mouse Anti-S100A6 Recombinant Antibody (clone PT2233) | IHC-P | Mouse IgG1, κ |
| VS3-CJ442 | Mouse Anti-S100A6 Recombinant Antibody (clone ABT-S100A6) | IHC-P | Mouse IgG1, κ |
| VS3-FY1298 | Recombinant Rabbit Anti-S100A6 Antibody (clone R01-8A4) | WB, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC490 | AbPlus™ Anti-S100A6 Magnetic Beads (VS-0724-YC490) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1993 | Anti-S100A6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6306 | Anti-Mouse S100A6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6307 | Anti-Rat S100A6 Immunohistochemistry Kit | IHC |
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