Recombinant Human Anti-SARS-CoV-2 S Antibody (clone S3H3) (CAT#: VS-0923-XY22)

The antibody S3H3 is a unique human recombinant antibody that binds to the SD1 region of the SARS-CoV-2 spike protein. S3H3 is able to cross-neutralize major variants of concern including Omicron and it remains highly effective against Omicron.

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ELISA

Figure 1 Binding activities of the S3H3 to recombinant S trimers of the WT, Delta and Omicron strains were tested by ELISA.

Figure 1 Binding activities of the S3H3 to recombinant S trimers of the WT, Delta and Omicron strains were tested by ELISA.

MAb S3H3 exhibited a high level binding activities to recombinant S trimers of the WT, Delta and Omicron strains.

Neut

Figure 2 Neutralization of the S3H3 towards WT, Delta and Omicron pseudoviruses.

Figure 2 Neutralization of the S3H3 towards WT, Delta and Omicron pseudoviruses.

MAb S3H3 exhibited potent neutralizing ability towards WT, Delta and Omicron pseudoviruses.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • SARS-CoV-2 Spike protein
  • Species Reactivity
  • SARS-CoV-2 (Omicron)
  • Clone
  • S3H3
  • Applications
  • ELISA, BLI, Neut
  • Related Disease
  • Coronavirus Disease 2019

Product Property

  • Purification
  • Protein A affinity purified
  • Purity
  • >95%
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Neutralization assay: All mAbs were fourfold serially diluted and tested by a pseudovirus Neutralization assayralization assay with human ACE2-overexpressing HEK 293T cells.

Target

  • Alternative Names
  • Severe acute respiratory syndrome coronavirus 2 Spike protein

Recommended Products

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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