Recombinant Anti-SLC17A8 Vesicular Antibody, EV Displayed (VS-0425-YC54)
CAT#: VS-0425-YC54
The Recombinant Anti-SLC17A8 Vesicular Antibody, EV Displayed (VS-0425-YC54) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SLC17A8-expressed cells or tissues. The SLC17A8 enables L-glutamate transmembrane transport, crucial for neurotransmitter functions, and is implicated in autosomal dominant deafness.
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SLC17A8
- Host Animal
- Rabbit
- Antibody Isotype
- IgG
- Species Reactivity
- Rat, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Solute carrier family 17 member 8
- Biological Process
- Hearing, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport
- Molecular Function
- Chloride channel, Ion channel
- Cellular Localization
- Endoplasmic reticulum
- Introduction
- Enables L-glutamate uniporter activity. Involved in L-glutamate transmembrane transport; positive regulation of glutamate uptake involved in transmission of nerve impulse; and regulation of acetylcholine uptake. Located in synaptic vesicle. Is active in glutamatergic synapse and synaptic vesicle membrane. Is expressed in brain; cochlear ganglion; and sensory organ. Used to study autosomal dominant nonsyndromic deafness 25. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Orthologous to human SLC17A8 (solute carrier family 17 member 8).
- Alternative Names
- Vglut3, Vgt3
- Gene ID
- 216227
- UniProt ID
- D3YTT3
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COA
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See other products for "SLC17A8"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2186MZ | Recombinant Mouse Anti-Human SLC17A8 Antibody (clone 4E22) | ELISA, WB | Mouse antibody |
| VS-0422-LC107 | Mouse Anti-Slc17a8 Recombinant Antibody (clone mN34/34.2) | ICC, WB, IF | Mouse IgG2a |
| VS-0422-LC108 | Rat Anti-Slc17a8 Recombinant Antibody (clone rtN34/34.2) | ICC, WB, IF | Rat IgG2b |
| VS-0422-LC109 | Rabbit Anti-Slc17a8 Recombinant Antibody (clone rN34/34.2) | ICC, WB, IF | Rabbit IgG |
| VS-0223-WK89 | Rabbit Anti-SLC17A8 Recombinant Antibody (VS-0223-WK89) | IHC, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6636 | Anti-SLC17A8 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6637 | Anti-Mouse SLC17A8 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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