Recombinant Anti-SLC17A8 Vesicular Antibody, EV Displayed (VS-0425-YC54) (CAT#: VS-0425-YC54)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• SLC17A8

• Host Animal
• Rabbit

• Antibody Isotype
• IgG

• Species Reactivity
• Rat, Mouse

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Solute carrier family 17 member 8

• Biological Process
• Hearing, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport

• Molecular Function
• Chloride channel, Ion channel

• Cellular Localization
• Endoplasmic reticulum

• Introduction
• Enables L-glutamate uniporter activity. Involved in L-glutamate transmembrane transport; positive regulation of glutamate uptake involved in transmission of nerve impulse; and regulation of acetylcholine uptake. Located in synaptic vesicle. Is active in glutamatergic synapse and synaptic vesicle membrane. Is expressed in brain; cochlear ganglion; and sensory organ. Used to study autosomal dominant nonsyndromic deafness 25. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Orthologous to human SLC17A8 (solute carrier family 17 member 8).

• Alternative Names
• Vglut3, Vgt3

• Gene ID
• 216227

• UniProt ID
• D3YTT3

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