Recombinant Anti-SLC1A5 Vesicular Antibody, EV Displayed (VS-0425-YC280) (CAT#: VS-0425-YC280)
The Recombinant Anti-SLC1A5 Vesicular Antibody, EV Displayed (VS-0425-YC280) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SLC1A5-expressed cells or tissues. The SLC1A5 is a sodium-dependent amino acid transporter, acting as a receptor for specific retroviruses.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35239/373_G10_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35239/373_G10_1_selected.jpg
Figure 2 Salivary gland
(High expression in salivary gland)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_B_3_1_val_selected.jpg
(High expression in salivary gland)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_B_3_1_val_selected.jpg
Figure 3 Epididymis
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_2_6.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_2_6.jpg
Figure 4 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_9_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_9_8.jpg
Figure 5 Colon
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_7_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_7_3.jpg
Figure 6 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Collecting ducts Staining: Low Intensity: Moderate Quantity: <25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Collecting ducts Staining: Low Intensity: Moderate Quantity: <25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_9_5.jpg
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105281-SLC1A5
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105281-SLC1A5
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SLC1A5
- Host Animal
- Human
- Antibody Isotype
- IgG
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Solute carrier family 1 member 5
- Biological Process
- Amino-acid transport, Antiport, Host-virus interaction, Symport, Transport
- Molecular Function
- Host cell receptor for virus entry, Receptor
- Cellular Localization
- Plasma membrane, Centriolar satellite, Basal body
- Introduction
- The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011]
- Alternative Names
- AAAT, ASCT2, M7V1, RDRC
- Gene ID
- 6510
- UniProt ID
- Q15758
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1002CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1002CLV) | ELISA | |
| TAB-1003CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1003CLV) | FC, Inhib | |
| TAB-1004CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1004CLV) | FC, Inhib | |
| TAB-1005CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1005CLV) | FC, Inhib | |
| TAB-1006CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1006CLV) | FC, Inhib |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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