Recombinant Anti-SLC29A1 Vesicular Antibody, EV Displayed (VS-0425-YC554)
CAT#: VS-0425-YC554
The Recombinant Anti-SLC29A1 Vesicular Antibody, EV Displayed (VS-0425-YC554) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SLC29A1-expressed cells or tissues. SLC29A1, a nucleoside transporter, mediates uptake for nucleotide synthesis and drug transport. This protein is categorized as equilibrative, sensitive to inhibition.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human colon
Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_A_5_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000112759-SLC29A1
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SLC29A1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Solute carrier family 29 member 1 (Augustine blood group)
- Biological Process
- Transport
- Introduction
- This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
- Alternative Names
- ENT1
- Gene ID
- 2030
- UniProt ID
- Q99808
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Datasheet
MSDS
COA
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See other products for "SLC29A1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2662z | Mouse Anti-SLC29A1 Recombinant Antibody (clone 37B3) | WB, ELISA, IF, IHC, IP | Mouse IgG2a, κ |
| MOB-164CQ | Mouse Anti-Human SLC29A1 Antibody | ELISA, WB, IP, IF, IHC-P | Mouse IgG2a, κ |
| HPAB-0540-YJ | Mouse Anti-SLC29A1 Recombinant Antibody (HPAB-0540-YJ) | ELISA, WB | Mouse IgG1 |
| HPAB-0541-YJ | Human Anti-SLC29A1 Recombinant Antibody (HPAB-0541-YJ) | ELISA, WB | Chimeric (mouse/human) IgG1 |
| VS13-YC1067 | Rabbit Anti-SLC29A1 Recombinant Antibody (VS13-YC1067) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0540-YJ-S(P) | Mouse Anti-SLC29A1 Recombinant Antibody; scFv Fragment (HPAB-0540-YJ-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0541-YJ-S(P) | Mouse Anti-SLC29A1 Recombinant Antibody; scFv Fragment (HPAB-0541-YJ-S(P)) | ELISA, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0540-YJ-F(E) | Mouse Anti-SLC29A1 Recombinant Antibody; Fab Fragment (HPAB-0540-YJ-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0541-YJ-F(E) | Human Anti-SLC29A1 Recombinant Antibody; Fab Fragment (HPAB-0541-YJ-F(E)) | ELISA, WB | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6659 | Anti-SLC29A1 Immunohistochemistry Kit | IHC |
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