Recombinant Anti-SLC2A8 Vesicular Antibody, EV Displayed (VS-0425-YC164)
CAT#: VS-0425-YC164
The Recombinant Anti-SLC2A8 Vesicular Antibody, EV Displayed (VS-0425-YC164) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SLC2A8-expressed cells or tissues. The SLC2A8 belongs to the solute carrier 2A family of glucose transporters, characterized by 12 transmembrane domains.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/1030_C8_3_selected.jpg
Normal Tissue
Figure 2 IHC staining of human testis
Immunohistochemical staining of human testis shows strong nuclear and cytoplasmic positivity in cells of seminiferus ducts.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/29605_A_5_6_selected.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/29605_A_7_4.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/29605_A_4_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (CACO-2, Hep G2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136856-SLC2A8
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Recombinant Antibody
- Application
- Cyt, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SLC2A8
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Solute carrier family 2 member 8
- Biological Process
- Sugar transport, Transport
- Cellular Localization
- Vesicles
- Introduction
- This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene.
- Alternative Names
- GLUT8, GLUTX1
- Gene ID
- 29988
- UniProt ID
- Q9NY64
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "SLC2A8"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-386CQ | Human Anti-SLC2A8 Recombinant Antibody (TAB-386CQ) | Cyt, FC, WB | Human IgG |
| TAB-386CQ-S(P) | Human Anti-SLC2A8 Recombinant Antibody; scFv Fragment (TAB-386CQ-S(P)) | ELISA, WB | Human scFv |
| TAB-386CQ-F(E) | Human Anti-SLC2A8 Recombinant Antibody; Fab Fragment (TAB-386CQ-F(E)) | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3300 | Hi-Affi™ Recombinant Rabbit Anti-SLC2A8 Monoclonal Antibody (DS3300AB) | WB | IgG |
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