Recombinant Anti-SLC6A6 Vesicular Antibody, EV Displayed (VS-0425-YC141) (CAT#: VS-0425-YC141)
The Recombinant Anti-SLC6A6 Vesicular Antibody, EV Displayed (VS-0425-YC141) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SLC6A6-expressed cells or tissues. The SLC6A6 is a multi-pass membrane protein transporting taurine and beta-alanine.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to cytosol & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/1636_E2_9_cr57bed6ae07246_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to cytosol & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/1636_E2_9_cr57bed6ae07246_selected.jpg
Figure 2 Small intestine
(High expression in small intestine)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_6_2_val_selected.jpg
(High expression in small intestine)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_6_2_val_selected.jpg
Figure 3 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_8_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_8_3.jpg
Figure 4 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_8_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_8_4.jpg
Figure 5 Kidney
(Collecting ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_8_5.jpg
(Collecting ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_8_5.jpg
Figure 6 Testis
(Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_6_6.jpg
(Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_6_6.jpg
Figure 7 Placenta
(Trophoblastic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_2_7.jpg
(Trophoblastic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15028/34643_A_2_7.jpg
Figure 8 RNA cell line category: Cell line enhanced (HeLa, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131389-SLC6A6
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131389-SLC6A6
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SLC6A6
- Host Animal
- Mouse
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein G
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Solute carrier family 6 member 6
- Biological Process
- Neurotransmitter transport, Symport, Transport
- Cellular Localization
- Cell Junctions, Cytosol
- Introduction
- This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Alternative Names
- TAUT
- Gene ID
- 6533
- UniProt ID
- P31641
Downloads
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|---|---|---|---|
| TAB-455CT | Anti-Human SLC6A6 Recombinant Antibody (4B9b) | ELISA, WB, FC | |
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| TAB-456CT-S(P) | Anti-Human SLC6A6 Recombinant Antibody scFv Fragment (5H12d ) | ELISA, WB, FC | |
| TAB-455CT-F(E) | Anti-Human SLC6A6 Recombinant Antibody Fab Fragment (4B9b) | ELISA, WB, FC | |
| TAB-456CT-F(E) | Anti-Human SLC6A6 Recombinant Antibody Fab Fragment (5H12d ) | ELISA, WB, FC |
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